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国家医院质量衡量标准的遵守情况与长期死亡率和再入院率的关联。

Association of National Hospital Quality Measure adherence with long-term mortality and readmissions.

机构信息

Center for Quality and Safety and Department of Surgery, Massachusetts General Hospital, 55 Fruit St., Boston, MA 02114, USA.

出版信息

BMJ Qual Saf. 2012 Apr;21(4):325-36. doi: 10.1136/bmjqs-2011-000615. Epub 2012 Mar 2.

Abstract

BACKGROUND

In existing studies, the association between adherence with recommended hospital care processes and subsequent outcomes has been inconsistent. This has substantial implications because process measure scores are used for accountability, quality improvement and reimbursement. Our investigation addresses methodological concerns with previous studies to better clarify the process-outcomes association for three common conditions.

METHODS

The study included all patients discharged from Massachusetts General Hospital between 1 July 2004 and 31 December 2007 with a principle diagnosis of acute myocardial infarction (AMI), heart failure (HF) or pneumonia (PN) who were eligible for at least one National Hospital Quality Measure. The number of patients analysed varied by measure (374 to 3020) depending on Centers for Medicare and Medicaid Services eligibility criteria. Hospital data were linked with state administrative data to determine mortality and readmissions. For patients with multiple admissions, the time-weighted impact of measure failures on mortality was estimated using exponential decay functions. All patients had follow-up for at least 1 year or until death or readmission. Cox models were used to estimate HRs adjusted for transfer status, age, gender, race, census block-group socioeconomic status, number of Elixhauser comorbidities, and do not resuscitate orders.

RESULTS

Adjusted survival and freedom from readmission for AMI and PN showed superior results for 100% and 50-99% adherence compared with 0-49% adherence. For HF, the results were inconsistent and sometimes paradoxical, although several individual measures (eg, ACE inhibitor/angiotensin receptor blockade) were associated with improved outcomes.

CONCLUSION

Adherence with recommended AMI and PN care processes is associated with improved long-term outcomes, whereas the results for HF measures are inconsistent. The evidence base for all process measures must be critically evaluated, including the strength of association between these care processes and outcomes in real-world populations. Some currently recommended processes may not be suitable as accountability measures.

摘要

背景

在现有研究中,遵医嘱接受医院治疗与后续结果之间的相关性并不一致。这具有重要意义,因为过程衡量标准分数被用于问责制、质量改进和报销。我们的调查解决了先前研究中的方法问题,以更好地阐明三种常见疾病的过程与结果之间的关联。

方法

该研究纳入了 2004 年 7 月 1 日至 2007 年 12 月 31 日期间从马萨诸塞州综合医院出院的所有患有急性心肌梗死(AMI)、心力衰竭(HF)或肺炎(PN)的患者,这些患者符合至少一项国家医院质量衡量标准的要求。根据医疗保险和医疗补助服务中心的资格标准,每种衡量标准的分析患者数量(374 至 3020 例)各不相同。医院数据与州行政数据相关联,以确定死亡率和再入院率。对于多次入院的患者,使用指数衰减函数估计衡量标准失败对死亡率的时间加权影响。所有患者的随访时间至少为 1 年或直至死亡或再入院。使用 Cox 模型来估计调整了转移状态、年龄、性别、种族、普查街区组社会经济地位、Elixhauser 合并症数量和不复苏医嘱的 HRs。

结果

AMI 和 PN 的调整后的生存率和无再入院率显示,与 0-49%的依从性相比,100%和 50-99%的依从性有更好的结果。对于 HF,结果不一致,有时甚至相互矛盾,尽管一些个别措施(如 ACE 抑制剂/血管紧张素受体阻滞剂)与改善结果相关。

结论

遵医嘱接受 AMI 和 PN 治疗与改善长期结果相关,而 HF 措施的结果不一致。必须严格评估所有过程衡量标准的证据基础,包括这些治疗过程与现实人群中结果之间的关联强度。一些目前推荐的过程可能不适合作为问责措施。

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