Department of Clinical Microbiology, Nicolaus Copernicus University in Toruń Ludwik Rydygier Collegium Medicum in Bydgoszcz, Poland.
Pol J Microbiol. 2011;60(4):345-9.
The present study investigated the ability of sub MICs of cefotaxime, imipenem and ciprofloxacin to interfere with adhesion of E. coli strains to polystyrene (selected polymer used in studies on microorganisms' adhesion). It was observed that cefotaxime and imipenem at 1/2 and 1/4 MICs decreased the adherence of E. coli strains to polystyrene significantly. 1/2, 1/4 and 1/8 MICs of ciprofloxacin generally decreased the adhesive properties of E. coli strains, but two E. coli strains showed a noticeable enhancement of adhesion after incubation at sub MICs of this antibiotic.
本研究旨在探讨亚最低抑菌浓度（sub MICs）的头孢噻肟、亚胺培南和环丙沙星对大肠杆菌菌株黏附于聚苯乙烯（用于微生物黏附研究的选定聚合物）能力的影响。结果表明，头孢噻肟和亚胺培南在 1/2 和 1/4 MIC 时显著降低了大肠杆菌菌株对聚苯乙烯的黏附能力。环丙沙星的 1/2、1/4 和 1/8 MIC 通常降低了大肠杆菌菌株的黏附特性，但两种大肠杆菌菌株在亚 MIC 环丙沙星孵育后，黏附能力明显增强。
