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颅内动脉瘤的 SILK 血流导向装置治疗:单中心 28 例患者 2 年经验。

Treatment of intra-cranial aneurysms with the SILK flow diverter: 2 years' experience with 28 patients at a single center.

机构信息

Department of Neurosurgery, Tel-Aviv Sourasky Medical Center, Israel.

出版信息

Acta Neurochir (Wien). 2012 Jun;154(6):979-87. doi: 10.1007/s00701-012-1316-2. Epub 2012 Mar 9.

Abstract

BACKGROUND

Flow diverters are recently developed stent-like endovascular devices developed to treat complex and non-coilable aneurysms. SILK is a type of flow diverter that has been used for nearly 3 years. Only sparse data about it are available. We would like to share our experience with this device.

METHODS

Twenty-eight patients were treated with SILK from October 2008 to October 2010. Thirty-one treatment sessions were performed for 32 aneurysms using 31 SILKs. Twenty have been treated with SILK only and eight with SILK and adjuvant stents. Twenty-six (86%) patients performed cross-sectional imaging (MRA/CTA) for follow-up. Eighteen (64%) patients had follow-up brain angiography.

RESULTS

In all patients the SILK could be deployed. No case of early or late aneurysmal rupture was noted. Five patients (17.8%) developed immediate clinical complications, which were permanent in three (10.7%). All the complications occurred in patients harboring aneurysms larger than 15 mm. In two other patients, occlusion of the SILK was noted with no clinical deficit. A complete or near-complete aneurysmal occlusion was found in brain angiography or cross-sectional imaging follow-up in 83.3% of the patients.

CONCLUSIONS

SILK is a relatively simple device to use, with a low rate of technical and clinical complications and a high short-term aneurysmal occlusion rate. In aneurysms smaller than 15 mm, the results are excellent. Results are also encouraging in the larger aneurysms, taking into consideration their complexity. The device characteristics and mainly its drawbacks must be well known by the users.

摘要

背景

血流导向装置是最近开发的一种支架样血管内设备,用于治疗复杂且不可圈闭的动脉瘤。SILK 是一种已使用近 3 年的血流导向装置。目前仅有少量关于它的数据。我们希望分享我们使用该装置的经验。

方法

2008 年 10 月至 2010 年 10 月,28 例患者接受 SILK 治疗。31 例 SILK 用于治疗 32 个动脉瘤,共进行了 31 次治疗。其中 20 例仅接受 SILK 治疗,8 例接受 SILK 联合辅助支架治疗。26 例(86%)患者进行了横断面成像(MRA/CTA)随访。18 例(64%)患者进行了脑血管造影随访。

结果

所有患者均能成功放置 SILK。未发现早期或晚期动脉瘤破裂病例。5 例(17.8%)患者出现即时临床并发症,其中 3 例(10.7%)为永久性并发症。所有并发症均发生在直径大于 15mm 的动脉瘤患者中。在另外 2 例患者中,发现 SILK 闭塞但无临床缺损。83.3%的患者在脑血管造影或横断面成像随访中发现完全或接近完全的动脉瘤闭塞。

结论

SILK 是一种相对简单的使用装置,具有较低的技术和临床并发症发生率以及较高的短期动脉瘤闭塞率。在直径小于 15mm 的动脉瘤中,结果非常出色。考虑到其复杂性,在较大的动脉瘤中结果也令人鼓舞。使用者必须充分了解该装置的特点和主要缺点。

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