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肉芽肿性与非肉芽肿性葡萄膜炎中角膜后沉着物的共聚焦扫描特征

Confocal Scan Features of Keratic Precipitates in Granulomatous versus Nongranulomatous Uveitis.

作者信息

Kanavi Mozhgan Rezaei, Soheilian Masoud

机构信息

Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

J Ophthalmic Vis Res. 2011 Oct;6(4):255-8.

Abstract

PURPOSE

To compare the morphologic features of keratic precipitates (KPs) by confocal microscopy in granulomatous versus nongranulomatous noninfectious uveitis.

METHODS

KP morphology was determined by confocal scan in patients with noninfectious granulomatous and noninfectious nongranulomatous uveitic cases.

RESULTS

One hundred and twenty-seven eyes of 90 subjects with noninfectious uveitis were studied. Thirty-nine eyes had granulomatous and 88 had nongranulomatous uveitis. Smooth-rounded KPs were significantly more common in the granulomatous subgroup (P<0.001) while cruciform and dendritiform KPs were more frequent in nongranulomatous uveitis (P<0.001 and P<0.005 respectively).

CONCLUSION

Confocal scan may be used as an adjunctive tool for differentiating granulomatous from nongranulomatous uveitis. Smooth-rounded KPs are strongly suggestive of granulomatous inflammation.

摘要

目的

通过共聚焦显微镜比较肉芽肿性与非肉芽肿性非感染性葡萄膜炎中角膜后沉着物(KPs)的形态学特征。

方法

对非感染性肉芽肿性和非感染性非肉芽肿性葡萄膜炎患者进行共聚焦扫描以确定KP形态。

结果

研究了90例非感染性葡萄膜炎患者的127只眼。39只眼为肉芽肿性葡萄膜炎,88只眼为非肉芽肿性葡萄膜炎。光滑圆形的KPs在肉芽肿性子组中明显更常见(P<0.001),而十字形和树枝状KPs在非肉芽肿性葡萄膜炎中更常见(分别为P<0.001和P<0.005)。

结论

共聚焦扫描可作为区分肉芽肿性与非肉芽肿性葡萄膜炎的辅助工具。光滑圆形的KPs强烈提示肉芽肿性炎症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b49/3306115/2e998718180a/jovr_v06_no4_06f1.jpg

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