Department of Obstetrics and Gynaecology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Neurourol Urodyn. 2012 Nov;31(8):1231-5. doi: 10.1002/nau.22239. Epub 2012 Mar 27.
Urethral pressure reflectometry (UPR) is a new method for measuring pressure and cross-sectional area in the urethra. Our aim was to investigate if the UPR parameters at rest and during squeeze were unchanged after TVT.
The technique enables measurement along the entire length of the urethra simultaneously and avoids the common artefacts encountered with conventional catheters. Twenty-two stress urinary incontinent women were included. The UPR polyurethane bag was placed in the urethra and connected to a pump and an acoustic transmitter. The bag was inflated, distending it accordingly, and the CA within the bag, and thus the urethra, was measured with acoustic reflectometry. Opening and closing pressure and elastance, and hysteresis were measured. "Relaxing" and "squeezing" measurements were conducted in the supine and standing position before and after TVT.
Subjective and objective cure rates were 82% and 100%, respectively. Maximum urine flow rate decreased from 31 to 18 ml/sec (P = 0.0002). Supine and standing relaxing urethral opening and closing pressures were unchanged. Supine opening elastance increased 18% (P = 0.04), which indicates an increased resistance against the opening of the urethra. Supine squeezing opening pressure decreased 10%.
UPR measurements confirmed that urethral opening pressure at rest is unchanged after TVT. The TVT somewhat improves the closure function by providing increased resistance against the dilation of the urethra, which probably explains the decreased maximum urine flow rate.
尿道压力反射测量法(UPR)是一种新的测量尿道压力和截面积的方法。我们的目的是研究 TVT 后,在休息和挤压时 UPR 参数是否保持不变。
该技术能够同时测量尿道的全长,并避免了传统导管常见的人为假象。纳入 22 例压力性尿失禁女性。将 UPR 聚氨酯袋置于尿道内,与泵和声学发射器相连。袋被充气,相应地扩张,袋内的 CA 即尿道得到测量。用声反射法测量尿道的开口和关闭压力、弹性和滞后。在 TVT 前后,仰卧位和站立位进行“放松”和“挤压”测量。
主观和客观治愈率分别为 82%和 100%。最大尿流率从 31 降至 18ml/sec(P=0.0002)。仰卧位和站立位放松时尿道的开口和关闭压力不变。仰卧位时尿道开口弹性增加 18%(P=0.04),这表明尿道的扩张阻力增加。仰卧位挤压时尿道开口压力下降 10%。
UPR 测量证实 TVT 后尿道休息时的开口压力保持不变。TVT 通过增加尿道扩张的阻力,在一定程度上改善了闭合功能,这可能解释了最大尿流率的降低。