Royal Adelaide Hospital/Institute of Medical and Veterinary Science, SA Health, Government of South Australia, Adelaide, South Australia 5000, Australia.
Gen Hosp Psychiatry. 2012 Jul-Aug;34(4):345-51. doi: 10.1016/j.genhosppsych.2012.02.006. Epub 2012 Mar 27.
The objective was to investigate changes in self-reported cardiovascular disease (CVD) burden associated with psychopathology for Australia from 2004 to 2008.
Data analyzed were from 32,073 participants aged ≥25 years from the 2004-2005 or 2007-2008 National Health Surveys. Lifetime diagnosis of CVD (heart attack or stroke) was by self-report. Psychopathology was determined by the 10-item Kessler Psychological Distress Scale (using scores ≥30) and use of antidepressants or antianxiety (AD/AA) medications.
The prevalence of CVD (4.1% to 4.5%, P=.045) had increased slightly from 2004 to 2008 for the general population, but not among those with psychopathology. On average, psychological distress only [odds ratio (OR) 2.00; 95% confidence interval, 1.52-2.62] and AD/AA medications with (OR 2.02; 1.41-2.88) and without psychological distress (OR 1.24; 1.00-1.55) were associated with increased odds of CVD over the 4-year period, independent of sociodemographic, lifestyle and chronic disease covariates. Both psychological distress only (OR 1.61; 1.15-2.25) and AD/AA medications with psychological distress (OR 1.62; 1.08-2.44) conferred higher odds of CVD than AD/AA medications without psychological distress.
In comparison to those without psychopathology, the odds of self-reported CVD were persistently higher among people with psychopathology from 2004 to 2008, particularly for psychological distress.
本研究旨在调查澳大利亚人群自 2004 年至 2008 年期间,与精神病理学相关的心血管疾病(CVD)负担的自我报告变化情况。
分析数据来源于参加 2004-2005 年或 2007-2008 年国家健康调查的 32073 名年龄≥25 岁的参与者。CVD(心脏病发作或中风)的终生诊断由自我报告确定。精神病理学通过 10 项 Kessler 心理困扰量表(得分≥30)和抗抑郁药或抗焦虑药(AD/AA)的使用来确定。
一般人群 CVD 的患病率(4.1%至 4.5%,P=.045)从 2004 年至 2008 年略有上升,但在有精神病理学的人群中没有增加。平均而言,仅心理困扰(优势比[OR]2.00;95%置信区间,1.52-2.62)和有(OR 2.02;1.41-2.88)和无(OR 1.24;1.00-1.55)心理困扰的 AD/AA 药物与 CVD 的发生风险增加相关,独立于社会人口统计学、生活方式和慢性疾病协变量。仅心理困扰(OR 1.61;1.15-2.25)和有心理困扰的 AD/AA 药物(OR 1.62;1.08-2.44)与无心理困扰的 AD/AA 药物相比,CVD 的发生风险更高。
与无精神病理学的人相比,2004 年至 2008 年期间,有精神病理学的人自我报告的 CVD 发病风险持续更高,尤其是与心理困扰有关。