Srivastava Ashutosh, Singh Mastan, Singh K P, Tripathi Piyush, Kumar Ram, Banerjee Gopa
Deptt of Microbiology, CSMM University, Lucknow.
J Commun Dis. 2010 Sep;42(3):171-7.
Present study was an attempt to study the prevalence of nonfermenter and its antibiotic susceptibility pattern at CSM Medical University, Lucknow. All the isolates and samples were selected from clinical specimens received in Bacteriology section, P.G. Depart of Microbiology, for culture. The observation were made on the nonfermenter isolates that can be isolated from clinical specimen using simple Laboratory media e.g. Blood Agar & Mac Conkey agar. All relevant history & information were recorded from the subjects. A total of 8340 specimen were screened for a period of one year. The prevalence of nonfermenters came to be 19.09% among all isolates. Most of spp. belongs to oxidase+ve group (77%). P. aeruginosa was found to be most common isolate (53%). Overall sensitivity profile for ciprofloxacin was 60%, P/T 58% & Amikacin 56%. Sensitivity of imepenem was 60% for multi-resistant isolates. The most resistant isolate was Sachrolytic Acinetobacter spp. The knowledge of synergism between drugs in context to different isolates may aid in effective therapy for these isolates.
本研究旨在探讨勒克瑙CSM医学院非发酵菌的流行情况及其抗生素敏感性模式。所有分离株和样本均选自微生物学研究生部细菌学科室接收的用于培养的临床标本。对使用简单实验室培养基(如血琼脂和麦康凯琼脂)从临床标本中分离出的非发酵菌分离株进行观察。记录了受试者的所有相关病史和信息。在一年的时间里共筛查了8340份标本。在所有分离株中,非发酵菌的流行率为19.09%。大多数菌种属于氧化酶阳性组(77%)。铜绿假单胞菌是最常见的分离株(53%)。环丙沙星的总体敏感性为60%,哌拉西林/他唑巴坦为58%,阿米卡星为56%。对多重耐药分离株,亚胺培南的敏感性为60%。最耐药的分离株是解糖嗜盐不动杆菌。了解不同分离株中药物之间的协同作用可能有助于对这些分离株进行有效治疗。