慢性静脉溃疡患者的维生素D缺乏症

Vitamin D deficiency in patients with chronic venous ulcers.

作者信息

Burkievcz Claudine Juliana C, Skare Thelma Larocca, Malafaia Osvaldo, Nassif Paulo Afonso Nunes, Ribas Claudia Stein Gomes, Santos Lorena Reis Pereira

机构信息

Faculdade Evangélica do Paraná, Hospital Universitário Evangélico de Curitiba, PR, Brasil.

出版信息

Rev Col Bras Cir. 2012;39(1):60-3.

PMID:22481708

Abstract

OBJECTIVE

To study if the prevalence of vitamin D deficiency in patients with venous leg ulcer is higher than in the control population.

METHODS

Serum levels of 25 hidroxi (OH)-vitamin D3 was studied by chemiluminescence in 27 patients with chronic venous ulcer and 58 controls at the Evangelical Hospital of Curitiba.

RESULTS

The levels of 25 OH-vitamin D3 were below 8 ng/dl in 11.1% of ulcer patients and 3.4% of controls; between 8 and 20 ng/dl in 46.1% of ulcer patients and 25.8% of controls; between 21 and 30 ng/dl in 22.2% of ulcer patients and 27.5% of controls and above 30 ng/dl in 43.1% of controls and 18.5% of ulcer patients (p=0.04).

CONCLUSION

There is an increased prevalence of vitamin D deficiency in patients with chronic venous leg ulcers.

摘要

目的

研究下肢静脉溃疡患者维生素D缺乏的患病率是否高于对照人群。

方法

在库里蒂巴福音医院，采用化学发光法对27例慢性静脉溃疡患者和58例对照者的血清25羟（OH）-维生素D3水平进行了研究。

结果

溃疡患者中11.1%的25 OH-维生素D3水平低于8 ng/dl，对照者中为3.4%；溃疡患者中46.1%的水平在8至20 ng/dl之间，对照者中为25.8%；溃疡患者中22.2%的水平在21至30 ng/dl之间，对照者中为27.5%；对照者中43.1%的水平高于30 ng/dl，溃疡患者中为18.5%（p=0.04）。