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[结膜炎治疗中的细菌学分析。1982年与2008年抗生素耐药性比较]

[Bacteriological analysis in the management of conjunctivitis. Comparison of antibiotic resistance between 1982 and 2008].

作者信息

Carreras B

机构信息

Departamento de Cirugía y sus especialidades, Universidad de Granada, España.

出版信息

Arch Soc Esp Oftalmol. 2012 Apr;87(4):107-11. doi: 10.1016/j.oftal.2011.11.017. Epub 2012 Mar 15.

DOI:10.1016/j.oftal.2011.11.017
PMID:22482893
Abstract

OBJECTIVE

To demonstrate the need for bacteriological analysis for the rational treatment of infections of the corneal surface, including conjunctivitis.

METHODS

The results of 1,970 consecutive bacteriological analysis obtained from 2001 to 2008 in patients with ocular hyperemia and discharge were analysed and compared with a similar study done in 1982 in the same geographical area.

RESULTS

Bacterial growth was obtained in 1,044 cases (53%). The most frequent bacteria were Staphylococci spp. (56.6%), followed by Streptococci spp. (21.4%), Haemophili spp. (12.1%), and other gram-negative bacteria (9.9%). No antibiotic was effective against all the bacteria isolated. The frequency of resistant bacteria against neomycin, tobramycin, erythromycin and gentamicin was significantly increased with respect to the study of 1982.

CONCLUSIONS

Bacteriological analysis of conjunctival specimens are necessary to ensure the choice of an effective antibiotic against bacteria of the ocular surface when the initial treatment fails.

摘要

目的

证明对包括结膜炎在内的角膜表面感染进行合理治疗时进行细菌学分析的必要性。

方法

分析了2001年至2008年连续从有眼部充血和分泌物的患者中获得的1970份细菌学分析结果,并与1982年在同一地理区域进行的类似研究进行比较。

结果

1044例(53%)获得细菌生长。最常见的细菌是葡萄球菌属(56.6%),其次是链球菌属(21.4%)、嗜血杆菌属(12.1%)和其他革兰氏阴性菌(9.9%)。没有一种抗生素对所有分离出的细菌都有效。与1982年的研究相比,对新霉素、妥布霉素、红霉素和庆大霉素耐药的细菌频率显著增加。

结论

当初始治疗失败时,结膜标本的细菌学分析对于确保选择针对眼表细菌的有效抗生素是必要的。

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