Rodríguez-Blanco M, Piñeiro A, Bande M, López-Valladares M J
Servicio de Oftalmología, Hospital de Conxo, Complexo Hospitalario Universitario de Santiago de Compostela, La Coruña, España.
Arch Soc Esp Oftalmol. 2012 Apr;87(4):122-4. doi: 10.1016/j.oftal.2011.07.015. Epub 2012 Jan 13.
We describe a 42 year-old patient who developed acute myopia and closed-angle glaucoma one week after beginning treatment with topiramate. Ultrasound biomicroscopy revealed a bilateral angle closure and choroidal effusion. The clinical findings resolved with withdrawal of the topiramate.
Topiramate may cause acute myopia and closure angle glaucoma in some patients due to a choroidal effusion. Ultrasound biomicroscopy seems to be a useful tool for monitoring the progression of the clinical lesions and their resolution when the drug is withdrawn.
我们描述了一名42岁的患者,在开始使用托吡酯治疗一周后出现急性近视和闭角型青光眼。超声生物显微镜检查显示双侧房角关闭和脉络膜积液。停用托吡酯后临床症状缓解。
托吡酯可能会因脉络膜积液导致一些患者出现急性近视和闭角型青光眼。超声生物显微镜检查似乎是监测临床病变进展以及停药后病变消退情况的有用工具。