Celik Mehmet, Sarıtaş Bülent, Tatar Tolga, Ozkan Murat, Akay Tankut, Aşlamacı Sait
Department of Cardiovascular Surgery, Faculty of Medicine, Başkent University, Ankara. Turkey.
Anadolu Kardiyol Derg. 2012 Jun;12(4):347-51. doi: 10.5152/akd.2012.099. Epub 2012 Apr 6.
Advanced age, dilated right atrium, increased preoperative pulmonary artery pressure, increased right atrial pressure, technique of operation, and poor ventricular function were reported to be risk factors for postoperative arrhythmia. Aim of this study is to determine the risk factor for postoperative arrhythmia after Fontan operation with regard to ventricle dominancy and hemodynamic parameters.
In this retrospective study, the data of the patients including age, weight, dominant ventricle, type of cardiac anomaly, previous operations, duration of cardiopulmonary bypass (CPB), duration of aortic clamping, cardiac rhythm, pulmonary artery pressure, the Nakata Index, systemic atrioventricular (AV) valve insufficiency were obtained from the hospital records, the echocardiographic files, and cardiac catheterization records. Patients were assigned to dominant left ventricle or dominant right ventricle groups. Statistical analysis was performed using the Mann-Whitney U test.
Arrhythmia was observed in 21 (52.5%) patients in the postoperative period. No postoperative arrhythmia was observed in patients with a right atrial pressure of <5 mmHg, whereas postoperative arrhythmias were observed in patients with a right atrial pressure of ≥5 mmHg (p<0.05). When the effects of preoperative and postoperative pulmonary artery pressures on postoperative arrhythmia were evaluated, postoperative arrhythmia was determined in only 2 (12.5%) of 8 patients with a preoperative mean pulmonary artery pressure of ≤9 mmHg, whereas postoperative arrhythmia was observed in 19 (59.3%) of 32 patients with a preoperative pulmonary artery pressure of ≥10 mmHg. A preoperative mean pulmonary artery pressure of >10 mmHg increased the risk of postoperative arrhythmia (p<0.02). Postoperative arrhythmia was determined in 8 (53%) of 15 patients with a dominant right ventricle, and in 13 (52%) of 25 patients with a dominant left ventricle (p>0.05).
While a preoperative mean pulmonary artery pressure of >10 mmHg and a preoperative right atrial pressure of >5 mmHg were the risk factors for postoperative arrhythmia in patients undergoing Fontan procedure, the right or left ventricular dominance was not a risk factor.
据报道,高龄、右心房扩大、术前肺动脉压升高、右心房压力升高、手术技术以及心室功能差是术后心律失常的危险因素。本研究的目的是确定在Fontan手术中,关于心室优势和血流动力学参数的术后心律失常危险因素。
在这项回顾性研究中,从医院记录、超声心动图文件和心导管检查记录中获取患者的数据,包括年龄、体重、优势心室、心脏畸形类型、既往手术、体外循环(CPB)持续时间、主动脉阻断持续时间、心律、肺动脉压、中田指数、体循环房室(AV)瓣关闭不全情况。患者被分为优势左心室组或优势右心室组。使用曼-惠特尼U检验进行统计分析。
术后21例(52.5%)患者出现心律失常。右心房压力<5 mmHg的患者未观察到术后心律失常,而右心房压力≥5 mmHg的患者观察到术后心律失常(p<0.05)。当评估术前和术后肺动脉压对术后心律失常的影响时,术前平均肺动脉压≤9 mmHg的8例患者中仅有2例(12.5%)出现术后心律失常,而术前肺动脉压≥10 mmHg的32例患者中有19例(59.3%)出现术后心律失常。术前平均肺动脉压>10 mmHg会增加术后心律失常的风险(p<0.02)。优势右心室的15例患者中有8例(53%)出现术后心律失常,优势左心室的25例患者中有13例(52%)出现术后心律失常(p>0.05)。
对于接受Fontan手术的患者,术前平均肺动脉压>10 mmHg和术前右心房压力>5 mmHg是术后心律失常的危险因素,而右心室或左心室优势不是危险因素。