基因簇可视化工具：用于保守基因簇可视化、探索和分析的工具。
GeneclusterViz: a tool for conserved gene cluster visualization, exploration and analysis.
机构信息
School of Informatics and Computing, Indiana University Bloomington, IN 47404, USA.
出版信息
Bioinformatics. 2012 Jun 1;28(11):1527-9. doi: 10.1093/bioinformatics/bts177. Epub 2012 Apr 11.
MOTIVATION
Gene clusters are arrangements of functionally related genes on a chromosome. In bacteria, it is expected that evolutionary pressures would conserve these arrangements due to the functional advantages they provide. Visualization of conserved gene clusters across multiple genomes provides key insights into their evolutionary histories. Therefore, a software tool that enables visualization and functional analyses of gene clusters would be a great asset to the biological research community.
RESULTS
We have developed GeneclusterViz, a Java-based tool that allows for the visualization, exploration and downstream analyses of conserved gene clusters across multiple genomes. GeneclusterViz combines an easy-to-use exploration interface for gene clusters with a host of other analysis features such as multiple sequence alignments, phylogenetic analyses and integration with the KEGG pathway database.
AVAILABILITY
http://biohealth.snu.ac.kr/GeneclusterViz/; http://microbial.informatics.indiana.edu/GeneclusterViz/
动机
基因簇是染色体上功能相关基因的排列。在细菌中，由于它们提供的功能优势，预计进化压力会保留这些排列。跨多个基因组可视化保守基因簇提供了它们进化历史的关键见解。因此，能够可视化和分析基因簇的软件工具将是生物研究界的宝贵资产。
结果
我们开发了 GeneclusterViz，这是一个基于 Java 的工具，允许跨多个基因组可视化、探索和下游分析保守基因簇。GeneclusterViz 将易于使用的基因簇探索界面与其他分析功能（如多重序列比对、系统发育分析以及与 KEGG 途径数据库的集成）结合在一起。
可用性
http://biohealth.snu.ac.kr/GeneclusterViz/; http://microbial.informatics.indiana.edu/GeneclusterViz/
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