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个体外科医生对冠状动脉旁路手术后再次出血风险的影响。

Individual surgeon's impact on the risk of re-exploration for excessive bleeding after coronary artery bypass surgery.

机构信息

Division of Cardiothoracic and Vascular Surgery, Department of Surgery, Oulu University Hospital, Oulu, Finland.

出版信息

J Cardiothorac Vasc Anesth. 2012 Aug;26(4):550-6. doi: 10.1053/j.jvca.2012.02.009. Epub 2012 Apr 11.

Abstract

OBJECTIVE

Excessive bleeding requiring re-exploration is a severe complication that may affect the outcome after coronary artery bypass grafting. The authors hypothesized that surgeon performance may contribute significantly to such a complication.

DESIGN

Retrospective.

SETTING

Tertiary referral center in a university hospital.

PARTICIPANTS

Two thousand one patients.

INTERVENTIONS

Isolated coronary artery bypass grafting.

RESULTS

Re-exploration for bleeding was performed in 113 patients (5.3%). Re-exploration was performed ≥3 days after surgery in 11 patients. The surgical site of bleeding was identified in 83 patients (73.5%). Rates of re-exploration for excessive bleeding ranged from 1.4% to 11.7% according to different surgeons (p < 0.0001). When adjusted for the additive European System for Cardiac Operative Risk Evaluation, re-exploration for bleeding was associated with increased risks of low-cardiac-output syndrome (odds ratio [OR] 2.239, 95% confidence interval [CI] 1.328-3.777), prolonged need for inotropes (OR 1.894, 95% CI 1.198-2.994), and an intensive care unit stay ≥5 days (OR 2.129, 95% CI 1.202-3.770). Logistic regression showed that an individual surgeon (p < 0.0001), preoperative body mass index <25 kg/m(2) (OR 2.733, 95% CI 2.145-3.481), and estimated glomerular filtration rate <30 mL/min/1.73 m(2) (OR 3.891, 95% CI 1.669-9.076) were independent predictors of re-exploration for excessive bleeding. An individual surgeon also was an independent predictor of a postoperative blood loss ≥1,600 mL.

CONCLUSIONS

An individual surgeon has a major impact on postoperative bleeding, and a meticulous surgical technique is expected to decrease significantly such a severe complication.

摘要

目的

需要再次探查的过度出血是一种严重的并发症,可能会影响冠状动脉旁路移植术后的结果。作者假设外科医生的表现可能对此类并发症有重大影响。

设计

回顾性。

地点

大学医院的三级转诊中心。

参与者

2100 名患者。

干预措施

单纯冠状动脉旁路移植术。

结果

113 名患者(5.3%)因出血行再次探查。11 名患者在术后≥3 天进行再次探查。在 83 名患者(73.5%)中确定了出血部位。根据不同外科医生,过度出血的再次探查率从 1.4%到 11.7%不等(p<0.0001)。当调整附加的欧洲心脏手术风险评估系统后,再次探查出血与低心输出综合征的风险增加相关(比值比[OR]2.239,95%置信区间[CI]1.328-3.777)、需要长时间使用正性肌力药(OR 1.894,95% CI 1.198-2.994)和重症监护病房住院时间≥5 天(OR 2.129,95% CI 1.202-3.770)。逻辑回归显示,个别外科医生(p<0.0001)、术前体重指数<25kg/m²(OR 2.733,95% CI 2.145-3.481)和估计肾小球滤过率<30mL/min/1.73m²(OR 3.891,95% CI 1.669-9.076)是再次探查过度出血的独立预测因子。个别外科医生也是术后出血量≥1600mL 的独立预测因子。

结论

个别外科医生对术后出血有重大影响,预计细致的手术技术将显著减少此类严重并发症。

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