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口服利巴韦林治疗小儿肝移植受者的呼吸道合胞病毒下呼吸道感染

Respiratory syncytial virus lower respiratory tract infection in a pediatric liver transplant recipient treated with oral ribavirin.

作者信息

Keck Megan, Mindru Cezarina, Kalil Andre C, Mercer David F, Florescu Diana F

机构信息

Department of Pharmaceutical and Nutrition Care, The Nebraska Medical Center, Omaha, NE 68198-1090, USA.

出版信息

Pediatr Transplant. 2012 Dec;16(8):E348-51. doi: 10.1111/j.1399-3046.2012.01700.x. Epub 2012 Apr 26.

Abstract

The mainstay of therapy for RSV disease is supportive care, although aerosolized ribavirin has been used to treat infants and young children with severe lower respiratory tract infections. Aerosolized ribavirin has adverse effects, high cost and teratogenic potential. We report the case of a pediatric liver transplant recipient diagnosed with lower respiratory RSV infection, who was successfully treated with oral ribavirin.

摘要

呼吸道合胞病毒(RSV)疾病治疗的主要方法是支持性护理,尽管雾化利巴韦林已被用于治疗患有严重下呼吸道感染的婴幼儿。雾化利巴韦林有不良反应、成本高且有致畸潜力。我们报告了一例小儿肝移植受者被诊断为下呼吸道RSV感染,经口服利巴韦林成功治疗的病例。

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