Division of Gastroenterology, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA.
Clin Liver Dis. 2012 May;16(2):421-33. doi: 10.1016/j.cld.2012.03.008.
Patients with chronic liver disease face greater risk of perioperative morbidity and mortality, with the greatest risk among patients with cirrhosis. Both the Child-Pugh score and the Model for End-Stage Liver Disease have been evaluated as predictors of postoperative mortality. Other comorbidities, age, and American Society of Anesthesiologists physical status classification are also important predictors of these outcomes. In patients with liver disease, elective surgeries should be delayed to allow complete evaluation of the severity of liver disease, including the role of transplantation in the event of hepatic decompensation postoperatively.
慢性肝脏疾病患者在围手术期面临更高的发病率和死亡率风险,其中肝硬化患者的风险最高。Child-Pugh 评分和终末期肝病模型都被评估为术后死亡率的预测因子。其他合并症、年龄和美国麻醉医师协会身体状况分类也是这些结果的重要预测因子。对于患有肝脏疾病的患者,应延迟择期手术,以充分评估肝脏疾病的严重程度,包括在术后肝功能失代偿的情况下移植的作用。