Urology Service, Hospital Nacional de Parapléjicos, Toledo, Spain.
Int J Impot Res. 2012 Jul-Aug;24(4):165-9. doi: 10.1038/ijir.2012.10. Epub 2012 May 3.
Electromyography (EMG) of the corpora cavernosa (CC-EMG) is able to record the activity of the erectile tissue during erection, and thus has been used as a diagnostic technique in patients with erectile dysfunction (ED). The present study examines the usefulness of the technique in the diagnosis of arterial ED. A cross-sectional study was made of 35 males with a mean age of 48.5 years (s.d. 11.34), referred to our center with ED for >1 year. The patients were subjected to CC-EMG and a penile Doppler ultrasound study following the injection of 20 μg of prostaglandin E1 (PGE1). The patients were divided into three groups according to their response to the intracavernous injection of PGE1: Group 1 (adequate erection and reduction/suppression of EMG activity); Group 2 (insufficient erection and persistence of EMG activity); and Group 3 (insufficient erection and reduction/suppression of EMG activity). Patient classification according to response to the intracavernous injection of PGE1 was as follows: Group 1: six patients (17%), Group 2: 18 patients (51%), and Group 3: 11 patients (31%). Patients diagnosed with arterial insufficiency according to Doppler ultrasound (systolic arterial peak velocity <30 mm s(-1) in both arteries) were significantly older than those without such damage (54.5 versus 41.8 years, respectively; s.d. 11.12). The patients in Group 3 showed a significantly lower maximum systolic velocity in both arteries than the subjects belonging to Group 2. Likewise, a statistically significant relationship was observed between the diagnosis of arterial insufficiency and patient classification in Group 3. The confirmation of insufficient erection associated with reduction/suppression of EMG activity showed a sensitivity of 66.7% (confidence interval between 50 and 84%) and a specificity of 92.9% (confidence interval between 84 and 100%) in the diagnosis of arterial ED. Owing to the high specificity of CC-EMG response to the injection of PGE1, this test is considered useful as a screening technique in the diagnosis of arterial ED.
海绵体肌电图（CC-EMG）能够记录勃起过程中勃起组织的活动，因此已被用作勃起功能障碍（ED）患者的诊断技术。本研究检查了该技术在动脉性 ED 诊断中的有用性。对 35 名平均年龄为 48.5 岁（标准差 11.34）的男性进行了一项横断面研究，这些男性因 ED 就诊时间超过 1 年。对这些患者进行了 CC-EMG 和前列腺素 E1（PGE1）注射后的阴茎多普勒超声研究。根据 PGE1 海绵体内注射后的反应，将患者分为三组：第 1 组（充分勃起，肌电图活动减少/抑制）；第 2 组（勃起不足，肌电图活动持续）；和第 3 组（勃起不足，肌电图活动减少/抑制）。根据 PGE1 海绵体内注射后的反应对患者进行分类如下：第 1 组：6 例（17%），第 2 组：18 例（51%），第 3 组：11 例（31%）。根据多普勒超声诊断为动脉功能不全的患者（两条动脉的收缩期动脉峰值速度<30 mm/s）明显比没有这种损伤的患者年龄更大（分别为 54.5 岁和 41.8 岁，标准差分别为 11.12 岁）。第 3 组患者的两条动脉的最大收缩速度明显低于属于第 2 组的患者。同样，在动脉功能不全的诊断和第 3 组的患者分类之间观察到统计学上的显著关系。与减少/抑制肌电图活动相关的勃起不足的确认显示动脉性 ED 诊断的灵敏度为 66.7%（置信区间为 50 至 84%），特异性为 92.9%（置信区间为 84 至 100%）。由于 CC-EMG 对 PGE1 注射的反应特异性高，因此该测试被认为是动脉性 ED 诊断的一种有用的筛选技术。
