Department of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, Japan.
Prenat Diagn. 2012 Jul;32(7):674-9. doi: 10.1002/pd.3886. Epub 2012 May 3.
This study aims to assess the attitudes toward non-invasive prenatal diagnosis (NIPD) and NIPD problems in clinical practice in Japan.
A mail-in survey using a self-reported questionnaire was conducted among pregnant women and health professionals. The questionnaire enquired about attitudes, concerns, and expectations regarding NIPD.
The responses from 252 respondents revealed that pregnant women have more positive attitudes toward NIPD than health professionals. In addition, there were wide discrepancies in concerns and expectations about NIPD, between medical professionals and pregnant women. The respondents with less NIPD knowledge had a more positive attitude toward the clinical application of NIPD. There was concern expressed by clinical geneticists whether an NIPD test should be performed or not when there is a lack of knowledge about the NIPD. All of the health professionals emphasized the importance of providing genetic counseling prior to and after the testing.
Pregnant women place importance on the safety and non-invasiveness of the NIPD tests, whereas medical professionals consider the diagnostic accuracy and reliability of the test to be the most important. Health professionals pointed out that the tests might be frequently performed without the pregnant women having adequate knowledge or counseling.
本研究旨在评估日本临床实践中对非侵入性产前诊断（NIPD）的态度和 NIPD 问题。
采用自报式问卷对孕妇和卫生专业人员进行邮寄调查。问卷询问了他们对 NIPD 的态度、关注和期望。
252 名受访者的回答显示，孕妇对 NIPD 的态度比卫生专业人员更为积极。此外，医疗专业人员和孕妇对 NIPD 的关注和期望存在很大差异。NIPD 知识较少的受访者对 NIPD 的临床应用持更为积极的态度。当对 NIPD 缺乏了解时，临床遗传学家对是否应进行 NIPD 检测表示担忧。所有卫生专业人员都强调在检测前和检测后提供遗传咨询的重要性。
孕妇重视 NIPD 检测的安全性和非侵入性，而医疗专业人员则认为检测的诊断准确性和可靠性更为重要。卫生专业人员指出，这些检测可能会在孕妇没有足够的知识或咨询的情况下频繁进行。
