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Age-related changes in CD8 T cell homeostasis and immunity to infection.
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Intrinsic and extrinsic contributors to defective CD8+ T cell responses with aging.
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Signal transduction changes in CD4 and CD8 T cell subpopulations with aging.
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Lifelong persistent viral infection alters the naive T cell pool, impairing CD8 T cell immunity in late life.
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Acute and chronic B cell depletion disrupts CD4+ and CD8+ T cell homeostasis and expansion during acute viral infection in mice.
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Impact of Aging, Cytomegalovirus Infection, and Long-Term Treatment for Human Immunodeficiency Virus on CD8 T-Cell Subsets.
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Epstein-Barr virus and multiple sclerosis: lesson learned to develop better nonhuman primate models.
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Immune age is correlated with decreased TCR clonal diversity and antibody response to SARS-CoV-2.
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Association of Immune Cell Subsets With Longevity: The Cardiovascular Health Study.
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Parenchymal and inflammatory responses to ozone exposure in the aging healthy and surfactant protein C mutant lung.
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The embodiment of the neighborhood socioeconomic environment in the architecture of the immune system.
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Age-associated alterations in CD8α+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium.
Aging Cell. 2012 Dec;11(6):968-77. doi: 10.1111/j.1474-9726.2012.00867.x. Epub 2012 Aug 30.
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Impaired NLRP3 inflammasome function in elderly mice during influenza infection is rescued by treatment with nigericin.
J Immunol. 2012 Mar 15;188(6):2815-24. doi: 10.4049/jimmunol.1103051. Epub 2012 Feb 10.
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Defective CD8 T cell responses in aged mice are due to quantitative and qualitative changes in virus-specific precursors.
J Immunol. 2012 Feb 15;188(4):1933-41. doi: 10.4049/jimmunol.1101098. Epub 2012 Jan 13.
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Virulence factors that modulate the cell biology of Listeria infection and the host response.
Adv Immunol. 2012;113:19-32. doi: 10.1016/B978-0-12-394590-7.00007-5.
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Polyfunctional T cells accumulate in large human cytomegalovirus-specific T cell responses.
J Virol. 2012 Jan;86(2):1001-9. doi: 10.1128/JVI.00873-11. Epub 2011 Nov 9.
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Report from the second cytomegalovirus and immunosenescence workshop.
Immun Ageing. 2011 Oct 28;8(1):10. doi: 10.1186/1742-4933-8-10.
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Premature age-related comorbidities among HIV-infected persons compared with the general population.
Clin Infect Dis. 2011 Dec;53(11):1120-6. doi: 10.1093/cid/cir627. Epub 2011 Oct 13.

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