玻璃体内注射雷珠单抗治疗与成人期卵黄样营养不良相关的脉络膜新生血管
[Intravitreal ranibizumab for choroidal neovascularisation associated with adult-onset vitelliform dystrophy].
作者信息
Prieto-Calvo E, Torrón-Fernández Blanco C, Egea-Estopiñán C, Güerri-Monclús N, Ferrer-Novella E, Ruiz-Moreno O, Pablo-Julvez L E
机构信息
Servicio de Oftalmología, Hospital Universitario Miguel Servet, Zaragoza, España.
出版信息
Arch Soc Esp Oftalmol. 2012 May;87(5):149-52. doi: 10.1016/j.oftal.2011.09.009. Epub 2012 Feb 9.
CASE REPORT
A 70-year-old male patient diagnosed with bilateral adult-onset vitelliform dystrophy presented with a sudden decrease of vision in his left eye associated with the appearance of an occult type of neovascular membrane. It was treated with intravitreal ranibizumab due to juxtafoveal location of the membrane. Two injections were needed to induce total regression of the lesion.
DISCUSSION
Intravitreal ranibizumab may be effective to induce morphological and functional improvement in cases of choroidal neovascularization secondary to adult-onset vitelliform foveomacular dystrophy. Further case series are required to confirm this observation.
病例报告
一名70岁男性患者被诊断为双侧成人型卵黄样营养不良，左眼视力突然下降，并伴有隐匿型新生血管膜的出现。由于该膜位于黄斑中心凹附近，故采用玻璃体内注射雷珠单抗进行治疗。需要两次注射才能使病变完全消退。
讨论
玻璃体内注射雷珠单抗可能对成人型卵黄样黄斑营养不良继发的脉络膜新生血管病例的形态和功能改善有效。需要更多的病例系列来证实这一观察结果。
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