Lange P, Balk-Møller S
Bispebjerg Hospital, København.
Ugeskr Laeger. 1990 Nov 19;152(47):3520-4.
Asbestos fibres have potent cancerogenic and fibrogenic properties and may lead to development of cancer and fibrosis in the lung parenchyma and pleura. The Danish Ministry of Employment has established rules which should prevent development of disease when working with asbestos in future but, on account of the very long latent period between exposure and development of asbestos-related disease, these conditions will still occur during the next 30-40 years. Primarily, the more benign pleural plaques will be concerned but serious disease such as bronchial carcinoma and pleural mesothelioma will occur in the future. When patients are encountered who present symptoms or objective/paraclinical findings which are compatible with disease produced by asbestos, it is important to remember that exposure to asbestos may be many decades ago and, particularly where the malignant conditions are concerned, exposure need not have been particularly massive or prolonged. All cases where asbestos-related disease is suspected should be notified to the insurance administration.
石棉纤维具有强大的致癌和致纤维化特性,可能导致肺实质和胸膜发生癌症和纤维化。丹麦就业部已制定规则,以防止未来在接触石棉工作时疾病的发生,但是,由于接触石棉与石棉相关疾病发生之间的潜伏期很长,这些病症在未来30至40年内仍会出现。主要涉及的是较为良性的胸膜斑,但未来也会出现诸如支气管癌和胸膜间皮瘤等严重疾病。当遇到有与石棉所致疾病相符的症状或客观/辅助临床检查结果的患者时,重要的是要记住接触石棉可能发生在几十年前,特别是对于恶性病症而言,接触不一定特别大量或持续时间长。所有怀疑与石棉相关疾病的病例都应通知保险管理部门。