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高效抗逆转录病毒治疗时代艾滋病危重症患者的超声心动图检查结果及其对预后的影响

Echocardiographic findings and their impact on outcomes of critically ill patients with AIDS in the era of HAART.

作者信息

Bajwa Abubakr A, Cury James D, Jones Lisa, Shujaat Adil, Usman Faisal

机构信息

Shands Hospital, College of Medicine, University of Florida, 655 West 8th Street, Jacksonville, FL 32209, USA.

出版信息

Pulm Med. 2012;2012:575793. doi: 10.1155/2012/575793. Epub 2012 Apr 9.

Abstract

Objective. To describe the echocardiographic findings in critically ill patients with AIDS and their impact on clinical outcome. Design. A retrospective chart review of consecutive AIDS patients over 18 years of age, who had a trans-thoracic echocardiogram performed during the course of intensive care unit stay over the course of 2 years at a tertiary care hospital. Main outcome measures. The prevalence of echocardiogram abnormalities in this population and its impact on ICU mortality, ICU length of stay, hospital mortality, hospital length of stay and 60 day survival. Results. Among 107 patients who met the inclusion criteria, an admission echocardiogram was performed in 62 (58%). The prevalence of cardiac abnormalities was 60%. The most common admission diagnosis was respiratory failure n = 27 (43%). The most common finding on echocardiogram was left ventricular (LV) dysfunction n = 31 (50%) followed by pulmonary hypertension n = 25 (40%). None of these findings had a significant impact on clinical outcomes. There was trend toward reduced 60 day survival among patients with depressed LV function. Conclusions. Although echocardiogram abnormalities were prevalent among this population none of these findings had a significant impact on ICU mortality or hospital mortality and ICU length of stay or hospital length of stay.

摘要

目的。描述重症艾滋病患者的超声心动图检查结果及其对临床结局的影响。设计。对一家三级护理医院在2年期间入住重症监护病房的连续18岁以上艾滋病患者进行回顾性病历审查,这些患者均接受了经胸超声心动图检查。主要结局指标。该人群中超声心动图异常的患病率及其对重症监护病房死亡率、重症监护病房住院时间、医院死亡率、医院住院时间和60天生存率的影响。结果。在符合纳入标准的107例患者中,62例(58%)进行了入院超声心动图检查。心脏异常的患病率为60%。最常见的入院诊断是呼吸衰竭,n = 27例(43%)。超声心动图最常见的发现是左心室(LV)功能障碍,n = 31例(50%),其次是肺动脉高压,n = 25例(40%)。这些发现均未对临床结局产生显著影响。左心室功能降低的患者60天生存率有下降趋势。结论。尽管该人群中超声心动图异常普遍存在,但这些发现均未对重症监护病房死亡率或医院死亡率以及重症监护病房住院时间或医院住院时间产生显著影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dba0/3337497/ddd875667fee/PM2012-575793.001.jpg

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