Boydell P, Pike R, Crossley D, Whitbread T
Animal Medical Centre Referral Services, 511 Wilbraham Rd, Chorlton, Manchester M21 0UB, England.
J Am Vet Med Assoc. 2000 Mar 15;216(6):872-4. doi: 10.2460/javma.2000.216.872.
To determine clinical findings, cytologic and histologic characteristics of salivary glands, and response to treatment with phenobarbital in dogs with clinical signs typical of sialadenosis.
Prospective study.
13 dogs with enlarged salivary glands.
Data were collected from dogs with clinical signs attributable to enlarged salivary glands. Salivary gland biopsy and cytologic specimens were examined. Dogs were treated with phenobarbital and monitored for response to treatment.
Clinical signs commonly associated with sialadenosis included retching and gulping. Substantial cellular changes were not detected by histologic or cytologic examination of enlarged salivary glands. Response to treatment with phenobarbital was rapid, although most dogs required continuous treatment to prevent recurrence of clinical signs.
Sialadenosis is a condition of unknown cause that may have been underdiagnosed in dogs. Criteria for diagnosis include typical clinical signs, enlarged salivary glands, and lack of substantial microscopic lesions. Response to treatment with phenobarbital is rapid.
确定患有涎腺肿大典型临床症状的犬的临床发现、涎腺的细胞学和组织学特征，以及对苯巴比妥治疗的反应。
前瞻性研究。
13只涎腺肿大的犬。
收集患有因涎腺肿大导致的临床症状的犬的数据。对涎腺活检和细胞学标本进行检查。用苯巴比妥治疗犬，并监测其对治疗的反应。
与涎腺肿大通常相关的临床症状包括干呕和吞咽。对肿大涎腺的组织学或细胞学检查未发现明显的细胞变化。对苯巴比妥治疗的反应迅速，尽管大多数犬需要持续治疗以防止临床症状复发。
涎腺肿大是一种病因不明的疾病，在犬中可能未得到充分诊断。诊断标准包括典型的临床症状、涎腺肿大以及缺乏明显的微观病变。对苯巴比妥治疗的反应迅速。
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