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用于放射治疗计划的(18)F-FDG PET/CT扫描的工作流程及辐射安全影响

Workflow and radiation safety implications of (18)F-FDG PET/CT scans for radiotherapy planning.

作者信息

Sam Sithoeun, Shon Ivan Ho, Vinod Shalini K, Lin Peter, Lin Michael

机构信息

Department of Nuclear Medicine and PET, Liverpool Hospital, Liverpool, Australia.

出版信息

J Nucl Med Technol. 2012 Sep;40(3):175-7. doi: 10.2967/jnmt.111.099440. Epub 2012 May 11.

DOI:10.2967/jnmt.111.099440
PMID:22582005
Abstract

UNLABELLED

The use of (18)F-FDG PET/CT for radiotherapy planning may lead to better tumor volume definition. Reproduction of the patient's position when setting up an (18)F-FDG PET/CT scan for radiotherapy planning is more accurate if a radiation therapist is involved. The aim of this study was to compare setup time and staff radiation dose between radiation therapists and nuclear medicine technologists.

METHODS

Forty patients with newly diagnosed head and neck or non-small cell lung cancer were prospectively recruited into this study. Twenty patients (10 with head and neck cancer and 10 with non-small cell lung cancer) underwent (18)F-FDG PET/CT for radiotherapy planning, and 20 patients (10 with head and neck cancer and 10 with non-small cell lung cancer) underwent (18)F-FDG PET/CT for staging. Setup time was measured, and a radiation monitor recorded the highest dose (μSv/h) to staff during setup.

RESULTS

For radiation therapists, the mean setup time for a lung scan (in min:s) was 5:22 ± 2:11 (range, 2:22-9:23), with a highest dose of 4.94 ± 3.78 μSv (range, 2.02-15.23 μSv), and the mean setup time for a head and neck scan was 4:49 ± 1:45 (range, 2:03-8:21), with a highest dose of 3.93 ± 1.45 μSv (range, 1.19-6.83 μSv). For nuclear medicine technologists, the mean setup time for a lung scan was 1:58 ± 0:24 (range, 1:17-2:38), with a highest dose of 3.30 ± 1.28 μSv (range, 1.92-5.47 μSv), and the mean setup time for a head and neck scan was 2:12 ± 0:38 (range, 1:03-3:16), with a highest dose of 3.10 ± 1.78 μSv (range, 1.56-7.49 μSv).

CONCLUSION

This study showed that setup time and operator radiation dose were greater for radiation therapists setting up planning (18)F-FDG PET/CT scans than for nuclear medicine technologists setting up routine (18)F-FDG PET/CT scans. These results have implications for scheduling of radiotherapy planning PET/CT; however, the additional radiation dose was not considered to be significant.

摘要

未标注

使用(18)F - FDG PET/CT进行放射治疗计划可能会使肿瘤体积的界定更精确。在为放射治疗计划设置(18)F - FDG PET/CT扫描时,如果有放射治疗师参与,患者体位的重现会更准确。本研究的目的是比较放射治疗师和核医学技术人员的摆位时间及工作人员所受辐射剂量。

方法

前瞻性招募40例新诊断的头颈部或非小细胞肺癌患者进入本研究。20例患者(10例头颈部癌和10例非小细胞肺癌)接受(18)F - FDG PET/CT用于放射治疗计划,20例患者(10例头颈部癌和10例非小细胞肺癌)接受(18)F - FDG PET/CT用于分期。测量摆位时间,并用辐射监测仪记录摆位过程中工作人员所接受的最高剂量(μSv/h)。

结果

对于放射治疗师,肺部扫描的平均摆位时间为5分22秒±2分11秒(范围2分22秒 - 9分23秒),最高剂量为4.94±3.78μSv(范围2.02 - 15.23μSv);头颈部扫描的平均摆位时间为4分49秒±1分45秒(范围2分03秒 - 8分21秒),最高剂量为3.93±1.45μSv(范围1.19 - 6.83μSv)。对于核医学技术人员,肺部扫描的平均摆位时间为1分58秒±0分24秒(范围1分17秒 - 2分38秒),最高剂量为3.30±1.28μSv(范围1.92 - 5.47μSv);头颈部扫描的平均摆位时间为2分12秒±0分38秒(范围1分03秒 - 3分16秒),最高剂量为3.10±1.78μSv(范围1.56 - 7.49μSv)。

结论

本研究表明,在设置用于放射治疗计划的(18)F - FDG PET/CT扫描时,放射治疗师的摆位时间和操作人员所受辐射剂量比设置常规(18)F - FDG PET/CT扫描的核医学技术人员要高。这些结果对放射治疗计划PET/CT的安排有影响;然而,额外的辐射剂量被认为不显著。

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