基于微植体的下颌前伸疗法治疗打鼾和阻塞性睡眠呼吸暂停：一项前瞻性研究。
Microimplant-based mandibular advancement therapy for the treatment of snoring and obstructive sleep apnea: a prospective study.
机构信息
Department of Orthodontics, School of Dentistry, Kyungpook National University, Daegu, Korea.
出版信息
Angle Orthod. 2012 Nov;82(6):978-84. doi: 10.2319/071311-449.1. Epub 2012 May 10.
OBJECTIVE
To investigate the efficacy of orthodontic microimplant-based mandibular advancement therapies for the treatment of snoring and obstructive sleep apnea (OSA) in adult patients.
MATERIALS AND METHODS
Ten adult OSA patients (seven men, three women; mean age 60.00 ± 9.25 years) were each treated with two mandibular orthodontic microimplants attached to a customized reverse face mask for mandibular advancement. Pretreatment and posttreatment outcome measures of microimplant mobility, apnea-hypopnea index, snoring, respiratory movement, and Epworth sleepiness scores were evaluated after 6 months.
RESULTS
Highly significant reductions in the apnea-hypopnea index, snoring, and sleep variables were observed. Sixteen of the 20 (80%) microimplants were stable and showed no mobility, and four (20%) demonstrated grade 1 or 2 mobility and required removal and reinsertion of a new microimplant.
CONCLUSIONS
Favorable reductions in sleep variables highlight the potential of microimplant-based mandibular advancement therapy as an alternative treatment modality for OSA patients who cannot tolerate continuous positive airway pressure and oral appliance therapy.
目的
探讨基于正畸微种植体的下颌前伸治疗成人鼾症和阻塞性睡眠呼吸暂停（OSA）的疗效。
材料和方法
10 例 OSA 成年患者（7 名男性，3 名女性；平均年龄 60.00±9.25 岁），每人使用两个下颌正畸微种植体和定制的反向面罩，以实现下颌前伸。6 个月后，评估微种植体移动度、呼吸暂停低通气指数、打鼾、呼吸运动和 Epworth 嗜睡评分等治疗前后的结果指标。
结果
观察到呼吸暂停低通气指数、打鼾和睡眠变量显著降低。20 个微种植体中有 16 个（80%）稳定且无移动度，4 个（20%）显示 1 级或 2 级移动度，需要移除并重新插入新的微种植体。
结论
睡眠变量的显著改善突显了基于微种植体的下颌前伸治疗作为不能耐受持续气道正压通气和口腔矫正器治疗的 OSA 患者的替代治疗方法的潜力。
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