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BMJ Case Rep. 2012 Apr 17;2012:bcr1120115160. doi: 10.1136/bcr.11.2011.5160.
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[Caudal appendage in a newborn infant].[一名新生儿的尾部附属物]
Bull Soc Med Afr Noire Lang Fr. 1973;18(3):382-4.

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本文引用的文献

1
Surgical treatment of a patient with human tail and multiple abnormalities of the spinal cord and column.一名患有人类尾巴及脊髓和脊柱多种异常患者的外科治疗。
Adv Orthop. 2011;2011:153797. doi: 10.4061/2011/153797. Epub 2010 Oct 18.
2
Human tail with noncontiguous intraspinal lipoma and spinal cord tethering: case report and embryologic discussion.伴有非连续性椎管内脂肪瘤和脊髓拴系的人类尾巴:病例报告及胚胎学讨论
Pediatr Neurosurg. 2005 Jan-Feb;41(1):35-40. doi: 10.1159/000084863.
3
A case of a human tail.一例人类尾巴病例。
Am J Dis Child. 1962 Jul;104:72-3. doi: 10.1001/archpedi.1962.02080030074010.
4
Human tails.人类的尾巴。
Plast Reconstr Surg Transplant Bull. 1960 Jun;25:618-21. doi: 10.1097/00006534-196006000-00009.
5
Three amphioxus Wnt genes (AmphiWnt3, AmphiWnt5, and AmphiWnt6) associated with the tail bud: the evolution of somitogenesis in chordates.三个与尾芽相关的文昌鱼Wnt基因(AmphiWnt3、AmphiWnt5和AmphiWnt6):脊索动物中体节发生的进化。
Dev Biol. 2001 Dec 1;240(1):262-73. doi: 10.1006/dbio.2001.0460.
6
Multiple pathways governing Cdx1 expression during murine development.在小鼠发育过程中调控Cdx1表达的多种途径。
Dev Biol. 2001 Nov 15;239(2):257-69. doi: 10.1006/dbio.2001.0446.
7
Clinical evaluation of cutaneous lesions of the back: spinal signatures that do not go away.背部皮肤病变的临床评估:不会消失的脊柱特征。
Clin Neurosurg. 1996;43:175-87.
8
Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development.对退化尾突变的分析表明,Wnt-3a基因剂量调节小鼠的轴向发育。
Genes Dev. 1996 Feb 1;10(3):313-24. doi: 10.1101/gad.10.3.313.
9
Wnt-3a regulates somite and tailbud formation in the mouse embryo.Wnt-3a调节小鼠胚胎中体节和尾芽的形成。
Genes Dev. 1994 Jan;8(2):174-89. doi: 10.1101/gad.8.2.174.
10
Atavisms and atavistic mutations.返祖现象与返祖突变。
Nat Genet. 1995 Jun;10(2):126-7. doi: 10.1038/ng0695-126.

一名患有尾部附器的婴儿。

An infant with caudal appendage.

作者信息

Shad Jimmy, Biswas Rakesh

机构信息

Department of General Surgery, People's College of Medical Sciences & Research Centre Bhopal, Bhopal, India.

出版信息

BMJ Case Rep. 2012 Apr 17;2012:bcr1120115160. doi: 10.1136/bcr.11.2011.5160.

DOI:10.1136/bcr.11.2011.5160
PMID:22604513
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3339178/
Abstract

There are several human atavisms that reflect our common genetic heritage with other mammals. One of the most striking is the existence of the rare 'true human tail'. It is a rare event with fewer than 40 cases reported in the literature. The authors report a case of an infant born with the true tail. A 3-month-old baby girl, presented with an 11 cm long tail, which was successfully surgically removed. Human embryos normally have a prenatal tail, which disappears in the course of embryogenesis by programmed cell death. Recent advances in genetic research reveal that 'of those organs lost, in evolution, most species carry 'genetic blue prints'. Thus, rarely the appearance of ancient organs like tail may be the result of re-expression of these switched off gene.

摘要

有几种人类返祖现象反映了我们与其他哺乳动物共有的基因遗传。其中最显著的一种是罕见的“真正的人类尾巴”的存在。这是一个罕见事件,文献报道的病例不到40例。作者报告了一例出生时带有真正尾巴的婴儿病例。一名3个月大的女婴,尾巴长11厘米,已通过手术成功切除。人类胚胎通常有一条产前尾巴,在胚胎发育过程中通过程序性细胞死亡而消失。遗传研究的最新进展表明,“在进化过程中失去的那些器官中,大多数物种都携带‘基因蓝图’”。因此,像尾巴这样的古老器官很少出现可能是这些被关闭基因重新表达的结果。