Atatürk Chest Diseases and Thoracic Surgery Education and Research Hospital, 06280, Ankara, Turkey.
Surg Endosc. 2012 Oct;26(10):2969-74. doi: 10.1007/s00464-012-2260-1. Epub 2012 May 19.
Symptomatic airway obstructions are common with endobronchial exophytic tumors and may result in lethal complications. Recently, a cryorecanalization procedure has emerged that plays a role in the immediate management of airway obstruction. This study was conducted to investigate the value of cryorecanalization for the immediate management of endobronchial obstructive pathology and to determine the factors that affect the success of the procedure.
We analyzed 40 patients with symptoms of airway obstruction who were admitted to our hospital from 2006 to 2010. Patients with exophytic stenosis due to primary bronchial or metastatic neoplasms who underwent cryorecanalization procedures were included. Patients were excluded if they had involvement of a major artery near the site of the intervention. The procedure was not performed on patients with coagulation abnormalities or thrombocyte count and aggregation problems. The data were collected retrospectively.
Successful cryorecanalization was achieved in 72.5 % of patients. We found that the success rate was mainly related to the presence of the distal involvement and the older age of obstruction. Restenosis rate was 17.2 %. [corrected] The mean survival time after the cryorecanalization procedure was 11 ± 12.7 months. No complications occurred in 14 patients. No severe bleeding was observed for any patients, and moderate hemorrhaging occurred in ten patients, which was stopped with an argon plasma coagulator. We experienced no intraoperative mortality.
Cryorecanalization is a successful and safe intervention for the immediate management of endobronchial stenosis. Appropriate patient selection and high success rates should be achieved after careful radiological assessments and with early management.
气道内外生肿瘤常导致气道阻塞症状,可能导致致命性并发症。近来,冷冻再通术已应用于气道阻塞的即刻处理,发挥着重要作用。本研究旨在探讨冷冻再通术即刻处理气道阻塞性病变的价值,并确定影响该操作成功率的因素。
我们分析了 2006 年至 2010 年间我院收治的 40 例有气道阻塞症状的患者。纳入接受冷冻再通术的原发性支气管或转移性肿瘤所致气道外生狭窄患者。排除病变部位附近有大血管受累、存在凝血功能异常、血小板计数和聚集问题的患者。所有数据均为回顾性收集。
72.5%的患者冷冻再通术成功。我们发现成功率主要与远端受累和阻塞的高龄有关。再狭窄率为 17.2%。[校正]冷冻再通术后的平均生存时间为 11±12.7 个月。14 例患者无并发症。无患者发生严重出血,10 例患者发生中度出血,用氩等离子凝固器止血。术中无死亡。
冷冻再通术是一种即刻处理气道内狭窄的有效且安全的介入方法。通过仔细的影像学评估和早期管理,可适当选择患者并获得较高的成功率。