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[肺循环停滞在心脏直视手术灌注后肺部并发症发生机制中的意义]

[Significance of the arrest of pulmonary circulation in the genesis of postperfusion pulmonary complications in open heart surgery].

作者信息

Kudriashov G M, Voinov V A, Shekhunov E D

出版信息

Grud Serdechnososudistaia Khir. 1990(9):41-3.

PMID:2261254
Abstract

The purpose of the work is to elucidate the importance of pulmonary circulation arrest during extracorporeal circulation in the development of microcirculatory disorders in the pulmonary tissue. Experiments showed that temporary arrest of pulmonary circulation under conditions of extracorporeal circulation is attended by the development of ischemia of the respiratory pulmonary tissue. The systemic blood flow in the arterio-arterial anastomoses between the pulmonary and bronchial arteries is incapable of providing the pulmonary tissue with blood. Ischemia of the parenchyma leads to disorders in the microvessels of the organ, the manifestation of which in the ischemic and postischemic, periods is determined by the duration of the pathologic effect. The data gained indicate the importance of developing methods for the prevention and treatment of ischemic and postischemic pulmonary microcirculatory disorders and determining the safe terms of pulmonary artery ischemia.

摘要

这项工作的目的是阐明体外循环期间肺循环停止在肺组织微循环障碍发展过程中的重要性。实验表明,体外循环条件下肺循环的暂时停止伴随着呼吸性肺组织缺血的发展。肺和支气管动脉之间的动脉-动脉吻合处的体循环血流无法为肺组织提供血液。实质缺血导致器官微血管紊乱,其在缺血期和缺血后期的表现取决于病理作用的持续时间。所获得的数据表明,开发预防和治疗缺血性及缺血后肺微循环障碍的方法以及确定肺动脉缺血的安全时限具有重要意义。

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