Gundgurthi Abhay, Kharb Sandeep, Dutta Manoj K, Garg M K, Khare Abhisek, Jacob M Joseph, Bhardwaj Reena
Department of Endocrinology, Army Hospital (Research and Referral), Delhi Cantonment, India.
Indian J Endocrinol Metab. 2012 May;16(3):431-5. doi: 10.4103/2230-8210.95699.
Adrenocortical cancers in childhood are very rare tumors. The tumors have varied presentation - either virilizing forms or presentation with Cushing's syndrome, or both. In children, due to the rapid development of symptoms they come to attention early, however, if not diagnosed and treated early can have a downhill course. The last decade has seen the emergence of new diagnostic imaging modalities. There is also intense ongoing research in newer treatment modalities as these tumors can be unresectable or have a high recurrence rate.
儿童肾上腺皮质癌是非常罕见的肿瘤。这些肿瘤有多种表现形式——要么是男性化形式,要么是库欣综合征表现,或者两者皆有。在儿童中,由于症状发展迅速,他们较早引起注意,然而,如果不及早诊断和治疗,病情会逐渐恶化。过去十年出现了新的诊断成像方式。对于更新的治疗方式也有深入的持续研究,因为这些肿瘤可能无法切除或复发率很高。