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可扩张钛笼在治疗颈椎病中的相关性研究。

Relevance of expandable titanium cage for the treatment of cervical spondylotic myelopathy.

机构信息

Department of Neurosurgery, Lille University Hospital, Lille, France.

出版信息

Eur Spine J. 2012 Aug;21(8):1545-50. doi: 10.1007/s00586-012-2380-2. Epub 2012 May 26.

Abstract

BACKGROUND

In patients with cervical spondylotic myelopathy, ventral disease and loss of physiological cervical lordosis are indications for anterior approach. As bone graft and titanium cage present many drawbacks, expandable titanium cage has been recently introduced for this indication. The authors present the clinical and radiological outcomes in patients undergoing the placement of an expandable cage in the treatment of spondylotic myelopathy with straight or kyphotic cervical spine alignment.

METHODS

This was a retrospective review of prospectively collected data. A total of 26 patients underwent cervical corpectomy and reconstruction using an expandable titanium cage and anterior plate between 2005 and 2008. Pain and functional disability were measured using VAS and mJOA preoperatively and at 3 months, 6 months, 1 year and 2 years. Kyphosis was measured using lateral radiographs at the same points of follow-up. Fusion was evaluated on flexion-extension radiographs at 2 years.

RESULTS

The mean VAS improved from 4.2 to 1.7 and the mean mJOA increased from 12.85 to 16.04 at 2 years postoperatively (p < 0.05). The mean kyphosis angle decreased from 17° to 2° at the last follow-up (p < 0.05). The fusion rate was 100% at 2 years. Three complications were reported including a transient dysphagia, an epidural hematoma and an early hardware migration.

CONCLUSION

Expandable titanium cage is an effective device, which achieves good clinical and radiological outcomes at a minimum 2-year follow-up.

摘要

背景

在患有脊髓型颈椎病的患者中,颈椎前侧病变和生理颈椎前凸丧失是采用前路手术的指征。由于骨移植物和钛笼存在许多缺点,最近已经引入了可扩张钛笼用于该适应证。作者介绍了在颈椎矢状位排列呈直或后凸的情况下,使用可扩张钛笼治疗脊髓型颈椎病的临床和影像学结果。

方法

这是一项前瞻性收集数据的回顾性研究。2005 年至 2008 年间,共有 26 例患者接受颈椎椎体次全切除和重建术,使用可扩张钛笼和前路钢板。在术前和术后 3 个月、6 个月、1 年和 2 年,使用视觉模拟评分(VAS)和日本骨科协会(mJOA)评分测量疼痛和功能障碍。在相同的随访点,使用侧位片测量后凸畸形。在术后 2 年,使用屈伸位 X 线片评估融合情况。

结果

术后 2 年,VAS 平均从 4.2 分改善至 1.7 分,mJOA 平均从 12.85 分增加至 16.04 分(p<0.05)。末次随访时,平均后凸角从 17°减小至 2°(p<0.05)。术后 2 年的融合率为 100%。报告了 3 例并发症,包括一过性吞咽困难、硬膜外血肿和早期内固定器迁移。

结论

在至少 2 年的随访中,可扩张钛笼是一种有效的治疗方法,可获得良好的临床和影像学结果。

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