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扩张型心肌病的二尖瓣手术治疗:现状与未来角色。

Mitral valve surgery for dilated cardiomyopathy: current status and future roles.

机构信息

Division of Cardiovascular Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

出版信息

Semin Thorac Cardiovasc Surg. 2012 Spring;24(1):51-8. doi: 10.1053/j.semtcvs.2012.04.008.

Abstract

There are a large number of patients with functional mitral regurgitation resulting from dilated cardiomyopathy. The decision between surgical correction and medical management of severe mitral regurgitation in heart failure can be difficult. The data regarding long-term benefits and mortality after surgical intervention are contradictory. Recent data suggest that mitral regurgitation can be surgically corrected in heart failure with symptomatic improvements and beneficial reverse remodeling. Contrary to prior beliefs, mitral valve repair can be performed safely with minimal postoperative mortality. Data from multi-institutional, randomized prospective trials will help to elucidate many of the questions and concerns regarding repair of severe functional mitral regurgitation.

摘要

有大量因扩张型心肌病导致的功能性二尖瓣反流患者。心力衰竭伴严重二尖瓣反流患者选择手术矫正还是内科治疗较为困难。关于手术干预的长期获益和死亡率的数据存在矛盾。近期数据表明,心力衰竭伴症状改善和有益的逆重构患者可行二尖瓣反流手术矫正。与既往观点相反,二尖瓣修复术可安全进行,术后死亡率较低。多中心、随机前瞻性试验的数据将有助于阐明关于严重功能性二尖瓣反流修复的许多问题和关注点。

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