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青少年特发性脊柱侧弯后路脊柱融合术联合或不联合术中细胞回收系统:一项回顾性比较研究

Posterior spinal fusion in adolescent idiopathic scoliosis with or without intraoperative cell salvage system: a retrospective comparison.

作者信息

Ersen Omer, Ekıncı Safak, Bılgıc Serkan, Kose Ozkan, Oguz Erbil, Sehırlıoglu Ali

机构信息

Department of Orthoapaedics and Traumatology, Gulhane Military Medical Academy, Ankara, Turkey.

出版信息

Musculoskelet Surg. 2012 Aug;96(2):107-10. doi: 10.1007/s12306-012-0203-6. Epub 2012 May 27.

DOI:10.1007/s12306-012-0203-6
PMID:22644881
Abstract

This study investigates efficacy and safety of routine cell salvage system use in adolescent idiopathic scoliosis patients undergoing primary posterior spinal fusion surgery with segmental spinal instrumentation. Forty-five consecutive adolescent idiopathic scoliosis patients undergoing posterior spinal fusion by two surgeons at a single hospital were studied. Intraoperative cell salvage system was used in 23 patients, and the control group was 22 patients who underwent surgery without cell salvage system. The cell salvage system was the Haemonetics Cell Saver 5. The primary outcome measures were intraoperative and perioperative allogeneic transfusion rate, difference between preoperative and discharge Hg and Hct levels. Average patient age was 14.65 ± 1.49 in cell saver group and 13.86 ± 2.0 in control group. In cell saver group, average intraoperative autotransfusion was 382.1 ± 175 ml. Average perioperative allogeneic blood transfusion need was 1.04 ± 0.7 unit in cell saver group and 2.5 ± 1.14 unit in control group. No transfusion reactions occurred in either group. Average hemoglobin level in cell saver group was 10.7 ± 0.86 and average hemoglobin level in control group was 10.7 ± 0.82 on discharge. Cell saver reduces perioperative transfusion rate in patients undergoing posterior spinal fusion for adolescent idiopathic scoliosis.

摘要

本研究调查了在接受一期后路脊柱融合术并使用节段性脊柱内固定器械的青少年特发性脊柱侧凸患者中常规使用细胞回收系统的有效性和安全性。对一家医院的两位外科医生连续进行后路脊柱融合术的45例青少年特发性脊柱侧凸患者进行了研究。23例患者术中使用了细胞回收系统,对照组为22例未使用细胞回收系统进行手术的患者。细胞回收系统为Haemonetics Cell Saver 5。主要观察指标为术中和围手术期异体输血率、术前与出院时血红蛋白(Hg)和血细胞比容(Hct)水平的差异。细胞回收机组患者平均年龄为14.65±1.49岁,对照组为13.86±2.0岁。细胞回收机组平均术中自体输血量为382.1±175 ml。细胞回收机组围手术期异体输血平均需求量为1.04±0.7单位,对照组为2.5±1.14单位。两组均未发生输血反应。出院时细胞回收机组平均血红蛋白水平为10.7±0.86,对照组平均血红蛋白水平为10.7±0.82。细胞回收系统可降低青少年特发性脊柱侧凸患者后路脊柱融合术的围手术期输血率。

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Posterior spinal fusion in adolescent idiopathic scoliosis with or without intraoperative cell salvage system: a retrospective comparison.青少年特发性脊柱侧弯后路脊柱融合术联合或不联合术中细胞回收系统:一项回顾性比较研究
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Eur Spine J. 2015 Feb;24(2):270-5. doi: 10.1007/s00586-014-3282-2. Epub 2014 Mar 30.
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Can Intra-Operative Cell Salvage Reduce the Rate of Allogeneic Transfusion in Pediatric Spinal Deformity Surgery?术中自体血回输能否降低小儿脊柱畸形手术中的异体输血率?
Global Spine J. 2025 Jun;15(5):2679-2686. doi: 10.1177/21925682241309287. Epub 2024 Dec 17.
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Utility of postoperative laboratory testing after posterior spinal fusion for adolescent idiopathic scoliosis.

本文引用的文献

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Blood loss in major spine surgery: are there effective measures to decrease massive hemorrhage in major spine fusion surgery?大型脊柱手术中的失血问题:在大型脊柱融合手术中,是否有减少大量出血的有效措施?
Spine (Phila Pa 1976). 2010 Apr 20;35(9 Suppl):S47-56. doi: 10.1097/BRS.0b013e3181d833f6.
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Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentation.术中细胞回收系统在接受后路脊柱融合和节段性脊柱器械固定的特发性脊柱侧凸患儿中的疗效。
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后路脊柱融合术后实验室检查的效用:青少年特发性脊柱侧凸。
Spine Deform. 2024 Mar;12(2):375-381. doi: 10.1007/s43390-023-00771-1. Epub 2023 Oct 26.
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A cost-effectiveness analysis of intraoperative autologous transfusion in adolescent idiopathic scoliosis surgery: a single-centre retrospective study.青少年特发性脊柱侧凸手术中术中自体输血的成本效果分析:一项单中心回顾性研究。
BMC Anesthesiol. 2023 Jun 17;23(1):211. doi: 10.1186/s12871-023-02180-3.
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Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study.单侧双通道内镜脊柱手术围手术期隐性失血的危险因素分析:一项回顾性多中心研究。
J Orthop Surg Res. 2021 Sep 15;16(1):559. doi: 10.1186/s13018-021-02698-7.
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Perioperative blood conservation strategies for pediatric scoliosis surgery.小儿脊柱侧凸手术的围手术期血液保护策略。
Spine Deform. 2021 Sep;9(5):1289-1302. doi: 10.1007/s43390-021-00351-1. Epub 2021 Apr 26.
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Cell salvage within adult and pediatric idiopathic scoliosis surgery: A random cross-sectional study.成人及小儿特发性脊柱侧弯手术中的自体血回输:一项随机横断面研究。
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Global Spine J. 2019 Dec;9(8):843-849. doi: 10.1177/2192568219837488. Epub 2019 Apr 14.
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Is cell salvage cost-effective in posterior arthrodesis for adolescent idiopathic scoliosis in the public health system?在公共卫生系统中,细胞回收用于青少年特发性脊柱侧弯后路融合术是否具有成本效益?
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Experience of Intraoperative Cell Salvage in Surgical Correction of Spinal Deformity: A Retrospective Review of 124 Patients.脊柱畸形手术矫正中术中细胞回收的经验:124例患者的回顾性研究
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成人腰椎融合术中回收式自体输血的疗效及成本效益
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The role of peri-operative cell salvage in instrumented anterior correction of thoracolumbar scoliosis: a case-controlled study.围手术期细胞回收在胸腰椎脊柱侧弯前路器械矫正中的作用:一项病例对照研究。
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Efficacy of intraoperative cell saver in decreasing postoperative blood transfusions in instrumented posterior lumbar fusion patients.术中血液回收机在减少后路腰椎融合内固定手术患者术后输血中的疗效
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The Cell Saver in adult lumbar fusion surgery: a cost-benefit outcomes study.成人腰椎融合手术中自体血回输装置的成本效益结果研究。
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Spine (Phila Pa 1976). 2004 Feb 1;29(3):233-8. doi: 10.1097/01.brs.0000109883.18015.b9.
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