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黏膜下结缔组织移植和引导组织再生的根覆盖稳定性:一项 30 个月的随访临床试验。

Root coverage stability of the subepithelial connective tissue graft and guided tissue regeneration: a 30-month follow-up clinical trial.

机构信息

Department of Diagnosis and Surgery, São Paulo State University (UNESP), School of Dentistry, Araraquara, SP, Brazil.

出版信息

J Dent. 2013 Feb;41(2):114-20. doi: 10.1016/j.jdent.2012.05.008. Epub 2012 May 29.

DOI:10.1016/j.jdent.2012.05.008
PMID:22652007
Abstract

OBJECTIVES

The aim of this study was to compare the long-term clinical effects produced by subepithelial connective tissue graft (SCTG) and guided tissue regeneration combined with demineralized freeze-dried bone allograft (GTR-DFDBA) in the treatment of gingival recessions in a 30-month follow-up clinical trial.

METHODS

Twenty-four defects were treated in 12 patients who presented canine or pre-molar Miller class I and/or II bilateral gingival recessions. GTR-DFDBA and SCTG treatments were performed in a randomized selection in a split-mouth design. The clinical measurements included root coverage (RC), gingival recession (GR), probing depth (PD), clinical attachment level (CAL) and keratinized tissue width (KTW). These clinical parameters were evaluated at baseline and after 6, 18 and 30months post-surgery.

RESULTS

The changes in RC, GR, PD and CAL did not show significant differences between groups (p>0.05). Both procedures promoted similar RC (GTR-DFDBA: 87% and SCTG: 95.5%) and similar reduction in GR (GTR-DFDBA: 3.25mm and SCTG: 3.9mm), PD (GTR-DFDBA: 1.6mm and SCTG: 1.2mm) and CAL (GTR-DFDBA: 4.9mm and SCTG: 5.0mm). The increase in KTW was significantly higher (p=0.02) in the SCTG group (3.5mm) than in the GTR-DFDBA group (2.4mm).

CONCLUSIONS

Both techniques for treatment of gingival recession (SCTG and GTR-DFDBA) lead to favourable and long-term stable results, but SCTG promoted a more favourable increase in keratinized tissue.

摘要

目的

本研究旨在比较结缔组织移植(SCTG)和引导组织再生联合脱矿冻干骨移植物(GTR-DFDBA)在治疗牙龈退缩中的长期临床效果,随访时间为 30 个月。

方法

12 例患者共 24 处牙间区或前磨牙区Ⅰ型和/或Ⅱ型双侧牙龈退缩,采用随机分组、分侧设计,分别采用 GTR-DFDBA 和 SCTG 治疗。临床评价包括根面覆盖率(RC)、牙龈退缩(GR)、探诊深度(PD)、临床附着水平(CAL)和角化组织宽度(KTW)。于基线、术后 6、18 和 30 个月进行临床评价。

结果

两组间 RC、GR、PD 和 CAL 的变化均无统计学差异(p>0.05)。两种方法均能获得较好的 RC(GTR-DFDBA:87%和 SCTG:95.5%)和 GR 减小(GTR-DFDBA:3.25mm 和 SCTG:3.9mm),PD 减小(GTR-DFDBA:1.6mm 和 SCTG:1.2mm)和 CAL 减小(GTR-DFDBA:4.9mm 和 SCTG:5.0mm)。SCTG 组 KTW 增加明显高于 GTR-DFDBA 组(p=0.02)(3.5mm 比 2.4mm)。

结论

两种治疗牙龈退缩的方法(SCTG 和 GTR-DFDBA)都能获得良好且长期稳定的效果,但 SCTG 更有利于角化组织的增加。

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