Duodecim. 2012;128(9):988-9.
This updated guideline focuses on the diagnosis and treatment of cutaneous melanoma. Diagnosis is based on the excision and histopathological analysis of a suspected skin lesion. Definitive surgery should be performed by an experienced surgical unit. Sentinel node biopsy is standard care in the case of clinically nodal-negative patients with intermediate-thickness or thick melanomas. Complete lymph node dissection is performed selectively in the case of sentinel-positive patients. Adjuvant therapy with interferon-alpha can be considered in high-risk patients. The follow-up schedule of an asymptomatic patient can be based on histopathological and clinical prognostic factors.
本更新指南聚焦于皮肤黑色素瘤的诊断与治疗。诊断基于对疑似皮肤病变的切除及组织病理学分析。确定性手术应由经验丰富的手术团队进行。对于临床淋巴结阴性的中厚或厚黑色素瘤患者,前哨淋巴结活检是标准治疗。前哨淋巴结阳性的患者则选择性地进行完整淋巴结清扫。高危患者可考虑使用α干扰素进行辅助治疗。无症状患者的随访计划可依据组织病理学和临床预后因素制定。