Department of Medicine, Howard University College of Medicine, Washington, DC, USA.
BMC Public Health. 2012 Jun 6;12:410. doi: 10.1186/1471-2458-12-410.
Magnitudes, geographic and racial variation in trends in coronary heart disease (CHD) mortality within the US require updating for health services and health disparities research. Therefore the aim of this study is to present data on these trends through 2007.
Data for CHD were analyzed using the US mortality files for 1999-2007 obtained from the US Centers for Disease Control and Prevention. Age-adjusted annual death rates were computed for non-Hispanic African Americans (AA) and European Americans (EA) aged 35-84 years. The direct method was used to standardize rates by age, using the 2000 US standard population. Joinpoint regression models were used to evaluate trends, expressed as annual percent change (APC).
For both AA men and women the magnitude in CHD mortality is higher compared to EA men and women, respectively. Between 1999 and 2007 the rate declined both in AA and in EA of both sexes in every geographic division; however, relative declines varied. For example, among men, relative average annual declines ranged from 3.2% to 4.7% in AA and from 4.4% to 5.5% in EA among geographic divisions. In women, rates declined more in later years of the decade and in women over 54 years. In 2007, age-adjusted death rate per 100,000 for CHD ranged from 93 in EA women in New England to 345 in AA men in the East North Central division. In EA, areas near the Ohio and lower Mississippi Rivers had above average rates. Disparities in trends by urbanization level were also found. For AA in the East North Central division, the APC was similar in large central metro (-4.2), large fringe metro (-4.3), medium metro urbanization strata (-4.4), and small metro (-3.9). APC was somewhat higher in the micropolitan/non-metro (-5.3), and especially the non-core/non-metro (-6.5). For EA in the East South Central division, the APC was higher in large central metro (-5.3), large fringe metro (-4.3) and medium metro urbanization strata (-5.1) than in small metro (-3.8), micropolitan/non-metro (-4.0), and non-core/non-metro (-3.3) urbanization strata.
Between 1999 and 2007, the level and rate of decline in CHD mortality displayed persistent disparities. Declines were greater in EA than AA racial groups. Rates were greater in the Ohio and Mississippi River than other geographic regions.
美国冠心病(CHD)死亡率的幅度、地理和种族变化趋势需要更新,以便为卫生服务和卫生差异研究提供信息。因此,本研究的目的是通过 2007 年呈现这些趋势的数据。
本研究使用了美国疾病控制与预防中心提供的 1999 年至 2007 年的美国死亡率文件,对 CHD 数据进行了分析。对年龄在 35-84 岁之间的非裔美国男性(AA)和欧洲裔美国男性(EA)计算了年龄调整后的年死亡率。使用 2000 年美国标准人口,直接法按年龄标准化比率,使用了标准方法。使用 Joinpoint 回归模型评估趋势,用年百分比变化(APC)表示。
AA 男性和女性的 CHD 死亡率明显高于 EA 男性和女性。1999 年至 2007 年期间,AA 和 EA 男女在每个地理区域的死亡率都有所下降;然而,相对下降幅度有所不同。例如,在男性中,相对年均下降幅度从 AA 的 3.2%到 4.7%和 EA 的 4.4%到 5.5%,在不同的地理区域有所不同。在女性中,这一比率在这十年的后期和 54 岁以上的女性中下降得更多。2007 年,EA 女性在新英格兰的 CHD 死亡率为每 10 万人 93 例,而在东中北部的 AA 男性中则为 345 例。在 EA 中,俄亥俄河和密西西比河附近的地区死亡率高于平均水平。城市化水平不同的地区,其趋势也存在差异。在东中北部地区,AA 的 APC 在大城市中心(-4.2)、大城市边缘(-4.3)、中等城市规模(-4.4)和小城市(-3.9)中相似。在大城市边缘(-5.3)、中等城市规模(-5.1)和非核心/非大都市(-6.5)中,微城市/非大都市(micropolitan/non-metro)的 APC 略高。在东中南部地区,EA 的 APC 在大城市中心(-5.3)、大城市边缘(-4.3)和中等城市规模(-5.1)中比小城市(-3.8)、微城市/非大都市(-4.0)和非核心/非大都市(-3.3)更高。
1999 年至 2007 年间,CHD 死亡率的水平和下降幅度持续存在差异。EA 种族群体的下降幅度大于 AA 种族群体。在俄亥俄州和密西西比河地区,死亡率高于其他地区。