Department of Heart and Great Vessels 'Attilio Reale', La Sapienza University of Rome.
J Cardiovasc Med (Hagerstown). 2012 Jul;13(7):454-6. doi: 10.2459/JCM.0b013e3283559af6.
Levosimendan increases the sensitivity of the heart to calcium and consequently exerts positive inotropic effects. Levosimendan is indicated in acutely decompensated severe congestive heart failure. We report that levosimendan infusion may induce myocardial ischemia in patients with acute heart failure.
左西孟旦增加心肌对钙离子的敏感性,从而发挥正性肌力作用。左西孟旦用于急性失代偿性严重充血性心力衰竭。我们报告称,左西孟旦输注可能会导致急性心力衰竭患者发生心肌缺血。