口腔黏膜淋巴上皮囊肿 120 例临床分析。

Clinical analysis of 120 cases of intraoral lymphoepithelial cyst.

机构信息

Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, School of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Apr;113(4):448-52. doi: 10.1016/j.tripleo.2011.02.051.

DOI:10.1016/j.tripleo.2011.02.051

PMID:22676924

Abstract

OBJECTIVE

The aim of this study was to analyze a single institution's experience in the clinical management of intraoral lymphoepithelial cyst (LEC).

STUDY DESIGN

From 1993 to 2010, a total of 120 consecutive patients with intraoral LEC underwent surgery and were retrospectively investigated regarding its clinical appearance, clinical differential diagnosis, treatment, and prognosis.

RESULTS

Of the 120 patients, 37 were male and 83 female, their ages ranging from 2 to 75 years with a mean of 44.1 years. The most common locations were the tongue (50%) and floor of mouth (38.3%). The course of disease ranged from 2 months to 10 years with a mean of 8.0 months, and 75.8% of the patients had a course of disease <6 months. Routine laboratory examinations were within normal limits. All patients underwent complete surgical removal of the lesions. During the follow-up period, no lesion recurrence occurred, and the quality of life of each patient was good.

CONCLUSIONS

The clinical characteristics of intraoral LEC are not specific and may be confused with other intraoral lesions. The first choice of treatment is surgical excision, which results in a good prognosis.

摘要

目的

本研究旨在分析单中心口腔内淋巴上皮囊肿（LEC）的临床诊治经验。

研究设计

1993 年至 2010 年，共 120 例口腔内 LEC 患者接受了手术治疗，对其临床表现、临床鉴别诊断、治疗和预后进行了回顾性调查。

结果

120 例患者中，男 37 例，女 83 例；年龄 2~75 岁，平均 44.1 岁。最常见的部位是舌（50%）和口底（38.3%）。病程 2 个月至 10 年，平均 8.0 个月，75.8%的患者病程<6 个月。常规实验室检查均在正常范围内。所有患者均行病变完整切除术。随访期间无病变复发，患者生活质量良好。