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非视轴区改良钕:钇铝石榴石激光治疗对Elschnig 珍珠样小体形态的影响。

Influence of a modified Nd:YAG laser treatment outside the visual axis on the morphology of Elschnig pearls.

机构信息

VIROS-Vienna Institute for Research in Ocular Surgery, A Karl Landsteiner Institute, Hanusch Hospital, Vienna, Austria.

出版信息

Ophthalmic Res. 2012;48(3):151-5. doi: 10.1159/000338751. Epub 2012 Jun 4.

Abstract

PURPOSE

To observe changes in posterior capsule opacification (PCO) after Nd:YAG treatment with and without opening the posterior lens capsule.

METHOD

This prospective randomized study included patients with regeneratory PCO. In substudy 1, a small low-energy Nd:YAG capsulotomy was performed (MiniYAG). In substudy 2, a low-energy Nd:YAG laser treatment without opening the lens capsule was performed (GentleYAG). Concerning analysis, in both substudies, the posterior capsule was divided into 4 quadrants and the quadrant where the Nd:YAG laser treatment was performed was randomly allocated. Change in PCO was analyzed using retroillumination images objectively (AQUA score: 0-10).

RESULTS

In total, 27 eyes of 25 patients were used for this study. In substudy 1, the mean amount of PCO (AQUA score) for the entire posterior capsule decreased significantly (p < 0.05, ANOVA) from 5.2 (SD: 1.6) before to 4.0 (SD: 1.9) immediately after the MiniYAG. In substudy 2, the mean amount of PCO (AQUA score) for the entire posterior capsule analyzed before and immediately after the GentleYAG was 5.1 (SD: 2.4) and 5.2 (SD: 2.3), respectively.

CONCLUSION

Performing a MiniYAG led to a significant PCO reduction. Gentle polishing of the posterior capsule resulted in a relevant reduction of PCO in one third of the patients.

摘要

目的

观察 Nd:YAG 治疗后是否打开后囊对后囊混浊(PCO)的影响。

方法

本前瞻性随机研究纳入了再生性 PCO 患者。在子研究 1 中,进行了小能量低强度 Nd:YAG 后囊切开术(MiniYAG)。在子研究 2 中,进行了不打开晶状体囊的低能量 Nd:YAG 激光治疗(GentleYAG)。分析时,在两个子研究中,后囊均分为 4 个象限,Nd:YAG 激光治疗的象限随机分配。使用后照光图像对 PCO 的变化进行客观分析(AQUA 评分:0-10)。

结果

本研究共纳入了 25 例患者的 27 只眼。在子研究 1 中,整个后囊的 PCO 平均量(AQUA 评分)从 MiniYAG 治疗前的 5.2(SD:1.6)显著降低(p < 0.05,ANOVA)至治疗后的 4.0(SD:1.9)。在子研究 2 中,整个后囊的 PCO 平均量(AQUA 评分)在 GentleYAG 治疗前和治疗后分别为 5.1(SD:2.4)和 5.2(SD:2.3)。

结论

进行 MiniYAG 可显著降低 PCO。对后囊进行温和抛光可使三分之一的患者的 PCO 显著降低。

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