VIROS-Vienna Institute for Research in Ocular Surgery, A Karl Landsteiner Institute, Hanusch Hospital, Vienna, Austria.
Ophthalmic Res. 2012;48(3):151-5. doi: 10.1159/000338751. Epub 2012 Jun 4.
To observe changes in posterior capsule opacification (PCO) after Nd:YAG treatment with and without opening the posterior lens capsule.
This prospective randomized study included patients with regeneratory PCO. In substudy 1, a small low-energy Nd:YAG capsulotomy was performed (MiniYAG). In substudy 2, a low-energy Nd:YAG laser treatment without opening the lens capsule was performed (GentleYAG). Concerning analysis, in both substudies, the posterior capsule was divided into 4 quadrants and the quadrant where the Nd:YAG laser treatment was performed was randomly allocated. Change in PCO was analyzed using retroillumination images objectively (AQUA score: 0-10).
In total, 27 eyes of 25 patients were used for this study. In substudy 1, the mean amount of PCO (AQUA score) for the entire posterior capsule decreased significantly (p < 0.05, ANOVA) from 5.2 (SD: 1.6) before to 4.0 (SD: 1.9) immediately after the MiniYAG. In substudy 2, the mean amount of PCO (AQUA score) for the entire posterior capsule analyzed before and immediately after the GentleYAG was 5.1 (SD: 2.4) and 5.2 (SD: 2.3), respectively.
Performing a MiniYAG led to a significant PCO reduction. Gentle polishing of the posterior capsule resulted in a relevant reduction of PCO in one third of the patients.
观察 Nd:YAG 治疗后是否打开后囊对后囊混浊(PCO)的影响。
本前瞻性随机研究纳入了再生性 PCO 患者。在子研究 1 中,进行了小能量低强度 Nd:YAG 后囊切开术(MiniYAG)。在子研究 2 中,进行了不打开晶状体囊的低能量 Nd:YAG 激光治疗(GentleYAG)。分析时,在两个子研究中,后囊均分为 4 个象限,Nd:YAG 激光治疗的象限随机分配。使用后照光图像对 PCO 的变化进行客观分析(AQUA 评分:0-10)。
本研究共纳入了 25 例患者的 27 只眼。在子研究 1 中,整个后囊的 PCO 平均量(AQUA 评分)从 MiniYAG 治疗前的 5.2(SD:1.6)显著降低(p < 0.05,ANOVA)至治疗后的 4.0(SD:1.9)。在子研究 2 中,整个后囊的 PCO 平均量(AQUA 评分)在 GentleYAG 治疗前和治疗后分别为 5.1(SD:2.4)和 5.2(SD:2.3)。
进行 MiniYAG 可显著降低 PCO。对后囊进行温和抛光可使三分之一的患者的 PCO 显著降低。