Department of Vector Biology and Control, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing 100071, P. R. China.
J Med Entomol. 2012 May;49(3):573-80. doi: 10.1603/me11239.
Odorant binding proteins (OBPs) play a critical role in mediating mosquito behaviors. In the current study, four AealOBP genes were cloned and sequenced. Basic Local Alignment Search Tool Program and phylogenetic analysis of the deduced amino acid sequences identified a unique putative ortholog in Aedes aegypti (L.) for each Aedes albopictus (Skuse) OBP. Quantitative analysis showed some AealOBPs with a strong female/male expression ratio, which we proposed to be involved in the host seeking of female mosquitoes. Other OBPs are expressed at higher levels in male antennae and are considered candidates for the detection of floral volatiles. The current study provides basis for further detailed molecular characterization of Ae. albopictus olfactory systems.
气味结合蛋白（OBPs）在介导蚊子行为方面起着关键作用。在本研究中，克隆并测序了四个 AealOBP 基因。基本局部比对搜索工具程序和推导的氨基酸序列的系统发育分析确定了埃及伊蚊（L.）中每个白纹伊蚊（Skuse）OBP 的独特假定直系同源物。定量分析显示，一些 AealOBPs 具有强烈的雌/雄表达比，我们认为这与雌蚊的宿主寻找有关。其他 OBPs 在雄触角中表达水平较高，被认为是检测花挥发物的候选物。本研究为进一步详细的白纹伊蚊嗅觉系统的分子特征提供了基础。
