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台湾地区乳腺癌患者中草药处方模式:一项基于人群的研究。

Prescription pattern of chinese herbal products for breast cancer in taiwan: a population-based study.

机构信息

Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei City 112, Taiwan.

出版信息

Evid Based Complement Alternat Med. 2012;2012:891893. doi: 10.1155/2012/891893. Epub 2012 May 28.

Abstract

Background. Chinese herbal products (CHPs) given as a therapy for symptom relief have gained widespread popularity among women with breast cancer. The aim of this study was to analyze the utilization of CHP among women with breast cancer in Taiwan. Methods. The usage, frequency of services, and CHP prescribed for breast cancer among women with breast cancer were evaluated, recruited from a randomly sampled cohort of 1,000,000 beneficiaries from the National Health Insurance Research Database. The logistic regression method was employed to estimate the odds ratios (ORs) for utilization of CHP. Results. 81.5 percent (N = 2, 236) of women with breast cancer utilized traditional Chinese medicine (TCM) and 18% of them sought TCM with the intent of treating their breast cancer. Jia-wei-xiao-yao-san (Augmented Rambling Powder) was the most frequently prescribed formula for treating breast cancer. Among the top 10 most frequently prescribed CHP for treating breast cancer, seven contained dang qui (Angelica sinensis-radix) and six contained ren shen (Panax ginseng-radix), which are reported to have potential beneficial synergistic effects on breast cancer cells. Conclusion. CHP containing dang qui (Angelica sinensis-radix) or ren shen (Panax ginseng-radix) are the most frequently prescribed for breast cancer and their effects should be taken into account by healthcare providers.

摘要

背景。作为缓解症状的疗法,中药产品(CHP)在乳腺癌女性中广受欢迎。本研究旨在分析台湾乳腺癌女性对 CHP 的使用情况。

方法。从国家健康保险研究数据库中随机抽取的 100 万名受益人的队列中招募乳腺癌女性,评估她们对 CHP 的使用、服务频率以及 CHP 治疗乳腺癌的情况。采用逻辑回归方法估计 CHP 使用的优势比(OR)。

结果。81.5%(N=2236)的乳腺癌女性使用了中药,其中 18%的人使用中药是为了治疗乳腺癌。加味逍遥散(Augmented Rambling Powder)是治疗乳腺癌最常用的方剂。在治疗乳腺癌的前 10 种最常开的 CHP 中,有 7 种含有当归(Angelica sinensis-radix),6 种含有人参(Panax ginseng-radix),据报道,它们对乳腺癌细胞具有潜在的有益协同作用。

结论。含有当归(Angelica sinensis-radix)或人参(Panax ginseng-radix)的 CHP 是治疗乳腺癌最常开的处方,医疗保健提供者应考虑其作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/555b/3368194/f65b98f65cd7/ECAM2012-891893.001.jpg

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