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本文引用的文献
1
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.
Nature. 2012 Apr 29;485(7397):195-200. doi: 10.1038/nature11019.
2
LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signaling.
Mol Cell Biol. 2012 Jun;32(11):2054-64. doi: 10.1128/MCB.00272-12. Epub 2012 Apr 2.
3
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways.
Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21188-93. doi: 10.1073/pnas.1118046108. Epub 2011 Dec 8.
4
LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling.
EMBO Rep. 2011 Sep 30;12(10):1055-61. doi: 10.1038/embor.2011.175.
5
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.
Nature. 2011 Jul 4;476(7360):293-7. doi: 10.1038/nature10337.
6
R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.
Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11452-7. doi: 10.1073/pnas.1106083108. Epub 2011 Jun 21.
7
Rspo3 binds syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis.
Dev Cell. 2011 Mar 15;20(3):303-14. doi: 10.1016/j.devcel.2011.01.006.
8
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts.
Nature. 2011 Jan 20;469(7330):415-8. doi: 10.1038/nature09637. Epub 2010 Nov 28.
9
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
Nat Genet. 2010 Nov;42(11):949-60. doi: 10.1038/ng.685. Epub 2010 Oct 10.
10
Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt.
EMBO J. 2010 Jul 7;29(13):2114-25. doi: 10.1038/emboj.2010.100. Epub 2010 May 21.
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