长春新碱诱发的单侧上睑下垂及对莫达非尼的意外反应。
Vincristine-induced unilateral ptosis with serendipitous response to modafinil.
作者信息
Revannasiddaiah Swaroop, Bhattacharyya Tapesh
机构信息
Department of Radiation Therapy and Oncology, Regional Cancer Center, Shimla, India.
出版信息
BMJ Case Rep. 2011 May 3;2011:bcr0720103178. doi: 10.1136/bcr.07.2010.3178.
Abstract
Here we describe a scenario of an atypical manifestation of vincristine-induced neurotoxicity, which responded serendipitously to modafinil. Atypical in that this patient had developed a uniocular ptosis, a rare manifestation of vincristine-induced neurotoxicity. The improvement in neurotoxicity after modafinil was started to alleviate morphine-induced sedation was quite noteworthy.
摘要
在此，我们描述了一例长春新碱诱导的神经毒性非典型表现的病例，该病例对莫达非尼意外产生了反应。说其非典型是因为该患者出现了单眼上睑下垂，这是长春新碱诱导的神经毒性的一种罕见表现。在开始使用莫达非尼以减轻吗啡诱导的镇静作用后，神经毒性得到改善，这一点相当值得注意。
相似文献
1
Vincristine-induced unilateral ptosis with serendipitous response to modafinil.长春新碱诱发的单侧上睑下垂及对莫达非尼的意外反应。
BMJ Case Rep. 2011 May 3;2011:bcr0720103178. doi: 10.1136/bcr.07.2010.3178.
2
[Vocal cord paralysis secondary to vincristine].
Rev Neurol (Paris). 2012 May;168(5):464-5. doi: 10.1016/j.neurol.2011.09.013. Epub 2012 Mar 3.
3
Chemotherapy-induced non-Hodgkin's lymphoma in a patient with Hodgkin's disease--a case report.霍奇金病患者化疗诱发非霍奇金淋巴瘤——病例报告
J Pak Med Assoc. 1996 Jan;46(1):14-5.
4
Combination of ibrutinib with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) for treatment-naive patients with CD20-positive B-cell non-Hodgkin lymphoma: a non-randomised, phase 1b study.伊布替尼联合利妥昔单抗、环磷酰胺、多柔比星、长春新碱和泼尼松（R-CHOP）治疗初治 CD20 阳性 B 细胞非霍奇金淋巴瘤患者：一项非随机、1b 期研究。
Lancet Oncol. 2014 Aug;15(9):1019-26. doi: 10.1016/S1470-2045(14)70311-0. Epub 2014 Jul 17.
5
Neutropenic enterocolitis.中性粒细胞减少性小肠结肠炎
Indian J Cancer. 2007 Jul-Sep;44(3):122-3. doi: 10.4103/0019-509x.38946.
6
Necrotizing leukoencephalopathy following CHOP chemotherapy.
Leuk Res. 2008 Oct;32(10):1611-4. doi: 10.1016/j.leukres.2008.02.014. Epub 2008 Apr 18.
7
Cardiovascular adverse events in patients with non-Hodgkin lymphoma treated with first-line cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or CHOP with rituximab (R-CHOP): a systematic review and meta-analysis.一线使用环磷酰胺、阿霉素、长春新碱和泼尼松（CHOP）或CHOP联合利妥昔单抗（R-CHOP）治疗的非霍奇金淋巴瘤患者的心血管不良事件：一项系统评价和荟萃分析。
Lancet Haematol. 2020 Apr;7(4):e295-e308. doi: 10.1016/S2352-3026(20)30031-4. Epub 2020 Mar 2.
8
Vincristine-induced unilateral ptosis in a child.长春新碱致儿童单侧上睑下垂。
Pediatr Neurol. 2009 Dec;41(6):461-3. doi: 10.1016/j.pediatrneurol.2009.07.005.
9
The effect of optimal treatment on elderly patients with aggressive non-Hodgkin's lymphoma: more patients treated with unaffected response rates.最佳治疗方案对老年侵袭性非霍奇金淋巴瘤患者的影响：更多患者接受治疗且缓解率未受影响。
Ann Hematol. 2001 Jul;80(7):406-10. doi: 10.1007/s002770100315.
10
Defining the cost of cure: infertility among female survivors of lymphoma.
Leuk Lymphoma. 2006 Apr;47(4):574-5.
本文引用的文献
1
Vincristine-induced unilateral ptosis in a child.长春新碱致儿童单侧上睑下垂。
Pediatr Neurol. 2009 Dec;41(6):461-3. doi: 10.1016/j.pediatrneurol.2009.07.005.
2
Approved and investigational uses of modafinil : an evidence-based review.莫达非尼的批准用途和研究用途：一项基于证据的综述。
Drugs. 2008;68(13):1803-39. doi: 10.2165/00003495-200868130-00003.
3
Involvement of central histaminergic systems in modafinil-induced but not methylphenidate-induced increases in locomotor activity in rats.中枢组胺能系统参与莫达非尼诱导而非哌甲酯诱导的大鼠运动活动增加。
Eur J Pharmacol. 2008 Jan 14;578(2-3):209-15. doi: 10.1016/j.ejphar.2007.09.009. Epub 2007 Sep 26.
4
Modafinil for excessive sleepiness associated with chronic shift work sleep disorder: effects on patient functioning and health-related quality of life.莫达非尼治疗与慢性倒班工作睡眠障碍相关的过度嗜睡：对患者功能及健康相关生活质量的影响。
Prim Care Companion J Clin Psychiatry. 2007;9(3):188-94. doi: 10.4088/pcc.v09n0304.
5
Walking with modafinil and its use in diplegic cerebral palsy: retrospective review.
J Child Neurol. 2006 Apr;21(4):294-7. doi: 10.1177/08830738060210042001.
6
A double-blind, placebo-controlled trial of modafinil for cocaine dependence.一项关于莫达非尼治疗可卡因依赖的双盲、安慰剂对照试验。
Neuropsychopharmacology. 2005 Jan;30(1):205-11. doi: 10.1038/sj.npp.1300600.
7
Isolated abducens nerve palsy induced by vincristine therapy.长春新碱治疗引起的孤立性展神经麻痹。
J AAPOS. 2004 Feb;8(1):69-71. doi: 10.1016/S1091853103003239.
8
Modafinil reduces excessive somnolence and enhances mood in patients with myotonic dystrophy.莫达非尼可减轻强直性肌营养不良患者的过度嗜睡并改善情绪。
Neurology. 2002 Dec 24;59(12):1876-80. doi: 10.1212/01.wnl.0000037481.08283.51.
9
Use of modafinil in spastic cerebral palsy.莫达非尼在痉挛型脑瘫中的应用。
J Child Neurol. 2002 Mar;17(3):169-72. doi: 10.1177/088307380201700303.
10
Chemotherapy-induced peripheral neuropathy.化疗引起的周围神经病变
J Neurol. 2002 Jan;249(1):9-17. doi: 10.1007/pl00007853.
Zotero 插件