与IgG抗GalNAc-GD1a抗体相关的亚急性运动轴索性神经病。
Subacute motor axonal neuropathy associated with the IgG anti-GalNAc-GD1a antibody.
作者信息
Goto Hirofumi, Fukudome Takayasu, Kusunoki Susumu, Matsuo Hidenori
机构信息
Department of Neurology, Arita Kyouritsu Hospital, Sage, Japan.
出版信息
BMJ Case Rep. 2011 Mar 29;2011:bcr1120103507. doi: 10.1136/bcr.11.2010.3507.
Abstract
A 14-year-old boy developed a distinct asymmetrical muscle atrophy and weakness with no sensory disturbance in the lower extremities after enteritis. He had an elevated titre of the IgG antibody against GalNAc-GD1a, but none of the others. A nerve conduction study revealed motor axonopathy. Intravenous immunoglobulin therapy improved the status gradually, with low titres of IgG anti-GalNAc-GD1a.
摘要
一名14岁男孩在患肠炎后出现明显的不对称性肌肉萎缩和下肢无力，无感觉障碍。他的抗GalNAc-GD1a IgG抗体滴度升高，但其他抗体均未升高。神经传导研究显示为运动轴索性神经病。静脉注射免疫球蛋白治疗使病情逐渐改善，抗GalNAc-GD1a IgG滴度降低。
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