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Delayed motor and sensory neuropathy in a patient with brainstem encephalitis.一名脑干脑炎患者出现迟发性运动和感觉神经病变。
J Neurol Sci. 2005 Jul 15;234(1-2):105-8. doi: 10.1016/j.jns.2005.02.011.
2
GalNAc-GD1a in human peripheral nerve: target sites of anti-ganglioside antibody.人外周神经中的N-乙酰半乳糖胺-神经节苷脂GD1a：抗神经节苷脂抗体的靶点部位
Neurology. 2003 Aug 26;61(4):465-70. doi: 10.1212/01.wnl.0000081229.88862.c6.
3
[A case of chronic pure motor neuropathy associated with anti-GalNAc-GD1a-IgM antibody].[一例与抗GalNAc-GD1a-IgM抗体相关的慢性纯运动性神经病病例]
No To Shinkei. 2003 Jul;55(7):609-12.
4
Peripheral neuropathies and anti-glycolipid antibodies.周围神经病变与抗糖脂抗体
Brain. 2002 Dec;125(Pt 12):2591-625. doi: 10.1093/brain/awf272.
5
Severe sensory ataxia and demyelinating polyneuropathy with IgM anti-GM2 and GalNAc-GD1A antibodies.伴有IgM抗GM2和GalNAc-GD1A抗体的严重感觉性共济失调和脱髓鞘性多发性神经病。
Muscle Nerve. 2002 Jun;25(6):828-36. doi: 10.1002/mus.10122.
6
IgM monoclonal antibody against terminal moiety of GM2, GalNAc-GD1a and GalNAc-GM1b from a pure motor chronic demyelinating polyneuropathy patient: effects on neurotransmitter release.来自一名纯运动性慢性脱髓鞘性多发性神经病患者的抗GM2、GalNAc-GD1a和GalNAc-GM1b末端部分的IgM单克隆抗体：对神经递质释放的影响
J Neuroimmunol. 2001 Sep 3;119(1):114-23. doi: 10.1016/s0165-5728(01)00373-3.
7
Chronic motor axonal neuropathy associated with antibodies monospecific for N-acetylgalactosaminyl GD1a.与N-乙酰半乳糖胺基GD1a单特异性抗体相关的慢性运动轴索性神经病
Muscle Nerve. 2000 May;23(5):702-6. doi: 10.1002/(sici)1097-4598(200005)23:5<702::aid-mus6>3.0.co;2-a.
8
Guillain-Barré syndrome with antibody to a ganglioside, N-acetylgalactosaminyl GD1a.伴有抗神经节苷脂N-乙酰半乳糖胺基GD1a抗体的吉兰-巴雷综合征
Brain. 2000 Jan;123 ( Pt 1):116-24. doi: 10.1093/brain/123.1.116.
9
Hyperreflexia in Guillain-Barré syndrome: relation with acute motor axonal neuropathy and anti-GM1 antibody.吉兰-巴雷综合征中的腱反射亢进：与急性运动轴索性神经病及抗GM1抗体的关系。
J Neurol Neurosurg Psychiatry. 1999 Aug;67(2):180-4. doi: 10.1136/jnnp.67.2.180.
10
Anti-GalNAc-GD1a antibody-associated Guillain-Barré syndrome with a predominantly distal weakness without cranial nerve impairment and sensory disturbance.抗GalNAc-GD1a抗体相关的吉兰-巴雷综合征，以远端肌无力为主，无颅神经损害和感觉障碍。
Ann Neurol. 1999 Jun;45(6):758-68.

与IgG抗GalNAc-GD1a抗体相关的亚急性运动轴索性神经病。

Subacute motor axonal neuropathy associated with the IgG anti-GalNAc-GD1a antibody.

作者信息

Goto Hirofumi, Fukudome Takayasu, Kusunoki Susumu, Matsuo Hidenori

机构信息

Department of Neurology, Arita Kyouritsu Hospital, Sage, Japan.

出版信息

BMJ Case Rep. 2011 Mar 29;2011:bcr1120103507. doi: 10.1136/bcr.11.2010.3507.

DOI:10.1136/bcr.11.2010.3507
PMID:22700488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3070378/
Abstract

A 14-year-old boy developed a distinct asymmetrical muscle atrophy and weakness with no sensory disturbance in the lower extremities after enteritis. He had an elevated titre of the IgG antibody against GalNAc-GD1a, but none of the others. A nerve conduction study revealed motor axonopathy. Intravenous immunoglobulin therapy improved the status gradually, with low titres of IgG anti-GalNAc-GD1a.

摘要

一名14岁男孩在患肠炎后出现明显的不对称性肌肉萎缩和下肢无力，无感觉障碍。他的抗GalNAc-GD1a IgG抗体滴度升高，但其他抗体均未升高。神经传导研究显示为运动轴索性神经病。静脉注射免疫球蛋白治疗使病情逐渐改善，抗GalNAc-GD1a IgG滴度降低。