The First Affiliated Hospital of Nanjing Medical University, Clinical Research Center, Nanjing, China.
Expert Opin Ther Pat. 2012 Jul;22(7):715-34. doi: 10.1517/13543776.2012.696100. Epub 2012 Jun 16.
The prevalence of allergic diseases has increased dramatically in recent decades. Therefore, there is a pressing need for the development of effective anti-allergic services worldwide.
In previous studies, the authors had analyzed a total of 789 anti-allergic patents granted in China from 1988 to 2008. Herein, they report a further 151 anti-allergic patents issued in China during 2009 - 2011. The current analysis covers the scientific progress in supporting anti-allergic patent applications and granted patent literature, in China, for the last 3 years.
The 151 anti-allergic patents granted from 2009 to 2011 mainly focus on seven types of products. They are: traditional Chinese medicines (TCM), plant extracts, biological products, synthetic compounds, pharmaceutical preparations, medical apparatus and new treatment modalities. Although the overall number of anti-allergic patent applications made between 2009 and 2011 in China is less than that of the USA and Europe, patents on TCM have increased. This suggests that there are demands for modernization of TCMs. Recently, studies of interesting new immunomodulators have also been conducted, and some of these are likely to represent clinically useful advances. In the last 3 years, several patents on these novel potential drugs have also been granted in China. The large number of anti-allergic patents issued in China, in recent times, suggests that the Chinese market is relatively competitive one that will help pharmaceutical companies make proper decisions for their research and development strategies.
近几十年来,过敏性疾病的患病率显著增加。因此,全球范围内迫切需要开发有效的抗过敏服务。
在之前的研究中,作者分析了 1988 年至 2008 年期间中国授予的总计 789 项抗过敏专利。在此,他们报告了 2009 年至 2011 年期间中国授予的另外 151 项抗过敏专利。目前的分析涵盖了过去 3 年来中国支持抗过敏专利申请和已授予专利文献的科学进展。
2009 年至 2011 年授予的 151 项抗过敏专利主要集中在七种产品上:中药、植物提取物、生物制品、合成化合物、药物制剂、医疗器械和新的治疗方式。尽管 2009 年至 2011 年中国抗过敏专利申请的总数少于美国和欧洲,但中药专利有所增加。这表明对中药现代化的需求。最近,对有趣的新型免疫调节剂的研究也在进行中,其中一些可能代表了临床上有用的进展。在过去的 3 年中,中国也授予了几项这些新型潜在药物的专利。中国近期授予了大量抗过敏专利,这表明中国市场竞争相对激烈,这将有助于制药公司为其研发战略做出正确决策。