Boyce J M
Department of Medicine, Miriam Hospital, Providence, Rhode Island 02906.
Infect Control Hosp Epidemiol. 1990 Dec;11(12):639-42. doi: 10.1086/646114.
In the period 1975 to 1981, methicillin-resistant Staphylococcus aureus (MRSA) emerged as an important nosocomial pathogen in tertiary care centers in the United States. To determine if the prevalence of this organism has continued to increase, a questionnaire was sent to hospital epidemiologists in 360 acute care hospitals. A total of 256 (71%) of the 360 individuals responded. Overall, 97% (246/256) of responding hospitals reported having patients with MRSA in the period 1987 through 1989. Respondents in 217 hospitals provided estimates of the number of cases seen in 1987, 1988 and 1989. The percentage of respondents reporting one or more patients with MRSA increased from 88% in 1987 to 96.3% in 1989 (p = .0008). The percent of respondents reporting large numbers (greater than or equal to 50) of cases per year increased from 18% in 1987 to 32% in 1989 (p = .0006). Increasing frequency of large outbreaks was observed in community, community-teaching, federal, municipal and university hospitals.
在1975年至1981年期间，耐甲氧西林金黄色葡萄球菌（MRSA）在美国三级护理中心成为一种重要的医院病原体。为了确定这种病原体的流行率是否持续上升，向360家急症护理医院的医院流行病学家发送了一份调查问卷。360人中共有256人（71%）回复。总体而言，97%（246/256）的回复医院报告在1987年至1989年期间有MRSA患者。217家医院的受访者提供了1987年、1988年和1989年所见病例数的估计。报告有一名或多名MRSA患者的受访者比例从1987年的88%增至1989年的96.3%（p = 0.0008）。报告每年有大量（大于或等于50例）病例的受访者比例从1987年的18%增至1989年的32%（p = 0.0006）。在社区医院、社区教学医院、联邦医院、市立医院和大学医院中，大规模暴发的频率不断增加。
