Division of Trauma, Department of Surgery, Wound Treatment and Research Center, University of California San Diego, 200 West Arbor Drive #8896, San Diego, CA 92103-8896, USA.
Clin Plast Surg. 2012 Jul;39(3):249-67. doi: 10.1016/j.cps.2012.05.006.
Wounds and damaged tissue become problematic when the tissue repair process does not proceed in a normal manner. Standard treatment of wounds entails topical dressings and devices in conjunction with good wound care practices. Good practices adequately support healing in most patients. Difficult, chronic, or recalcitrant wounds may require the use of more advanced technologies. Wounds that are full thickness or present with the absence of a matrix, may particularly benefit from regenerative materials. This article focuses on the use of cellular and acellular materials as well as chemical constructs to support granulation, tissue repair, and wound closure.
当组织修复过程不能正常进行时,伤口和受损组织就会成为问题。伤口的标准治疗包括局部敷料和装置以及良好的伤口护理措施。良好的治疗方法可以为大多数患者提供足够的支持以促进愈合。复杂、慢性或难治性伤口可能需要使用更先进的技术。全层伤口或缺乏基质的伤口可能特别受益于再生材料。本文重点介绍细胞和去细胞材料以及化学构建物的使用,以支持肉芽组织形成、组织修复和伤口闭合。