Department of Surgery, Vanderbilt University, Nashville, TN, USA.
Physiol Meas. 2012 Jul;33(7):1171-9. doi: 10.1088/0967-3334/33/7/1171. Epub 2012 Jun 27.
We measured gastric slow wave activity simultaneously with a Superconducting Quantum Interference Device (SQUID) magnetometer, mucosal electrodes and cutaneous electrodes in 18 normal human subjects (11 women and 7 men). We processed signals with Fourier spectral analysis and SOBI blind-source separation techniques. We observed a high waveform correlation between the mucosal electromyogram (EMG) and multichannel SQUID magnetogastrogram (MGG). There was a lower waveform correlation between the mucosal EMG and cutaneous electrogastrogram (EGG), but the correlation improved with the application of SOBI. There was also a high correlation between the frequency of the electrical activity recorded in the MGG and in mucosal electrodes (r = 0.97). We concluded that SQUID magnetometers noninvasively record gastric slow wave activity that is highly correlated with the activity recorded by invasive mucosal electrodes.
我们在 18 名正常人体（11 名女性和 7 名男性）中同时使用超导量子干涉仪（SQUID）磁强计、黏膜电极和皮肤电极测量胃慢波活动。我们使用傅里叶谱分析和 SOBI 盲源分离技术处理信号。我们观察到黏膜肌电图（EMG）和多通道 SQUID 胃磁图（MGG）之间具有很高的波形相关性。黏膜 EMG 和皮肤胃电图（EGG）之间的波形相关性较低，但应用 SOBI 后相关性得到改善。在 MGG 和黏膜电极记录的电活动的频率之间也存在高度相关性（r = 0.97）。我们得出结论，SQUID 磁强计非侵入性地记录胃慢波活动，与侵入性黏膜电极记录的活动高度相关。
