[Role of alkaline phosphatase Regan isoenzyme in prognosis of patients with osteosarcoma].
作者信息
Tucci A, Saviano C, Del Prete S
机构信息
I Divisione di Ortopedia e Traumatologia, Ospedale Santobono, Napoli.
出版信息
Medicina (Firenze). 1990 Apr-Jun;10(2):158-60.
PMID:2273951
Abstract
The presence of Regan isoenzyme (the heat stable fraction of alkaline phosphatase) in serum of patients with osteosarcoma has been proposed as a prognostic factor indicating the metastatic evolution of the disease. This work reports on 9 patients with osteosarcoma. In 4 of them Regan isoenzyme was present 4, 6, 12, and 16 months before clinical-instrumental evidence of lung metastases. These results further support the significance of this isoenzyme as a marker of relapse in an early subclinical stage.
摘要
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