Chen Qingyong, Wu Li Jun, Hu Huizhen, Song Jia, Wu Yuquan, Yan Jie, Shi Jianguo
Department of Respiratory Oncology, The 117th Hospital of PLA, Hangzhou 310013, P.R. China.
Oncol Lett. 2012 Mar;3(3):646-648. doi: 10.3892/ol.2011.524. Epub 2011 Dec 14.
Pulmonary sclerosing hemangioma (PSH) is a relatively rare benign neoplasm, often asymptomatic and presenting as a solitary pulmonary nodule on radiological imaging studies. In the present case report, we examined a case of PSH in a young adult female, and reviewed the literature pertaining to PSH with an emphasis on (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)FDG PET/CT) and pathology. Immunohistochemical staining was also performed to confirm the diagnosis of sclerosing hemangioma. The results revealed that the tumor cells were immunopositive for epithelial membrane antigen, thyroid transcription factor-1 and vimentin and cytoskeleton 7. The patient recovered and was discharged. Thus, (18)FDG PET/CT may be used in the diagnosis of a solitary benign pulmonary nodule.
肺硬化性血管瘤(PSH)是一种相对罕见的良性肿瘤,通常无症状,在影像学检查中表现为孤立性肺结节。在本病例报告中,我们检查了一名年轻成年女性的PSH病例,并回顾了与PSH相关的文献,重点关注氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描(18F-FDG PET/CT)和病理学。还进行了免疫组织化学染色以确诊硬化性血管瘤。结果显示,肿瘤细胞上皮膜抗原、甲状腺转录因子-1、波形蛋白和细胞角蛋白7呈免疫阳性。患者康复出院。因此,18F-FDG PET/CT可用于孤立性良性肺结节的诊断。