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类风湿性多肌痛患者胸椎硬膜外炎性假瘤。

Epidural inflammatory pseudotumor in the thoracic spine in a patient with polymyalgia rheumatica.

机构信息

Department of Orthopaedic Surgery, Kanazawa University School of Medicine, 13-1 Takara-machi, Kanazawa 920-8641, Japan.

出版信息

Spine J. 2012 Jun;12(6):e1-4. doi: 10.1016/j.spinee.2012.06.001. Epub 2012 Jun 30.

Abstract

BACKGROUND CONTEXT

Only six previous cases of epidural inflammatory psedotumor in the spine have been reported. None of them were seen in the course of polymyalgia rheumatica (PMR).

PURPOSE

To describe a rare case of epidural inflammatory pseudotumor in the thoracic spine in a patient with PMR.

STUDY DESIGN

Case report.

METHODS

A 63-year-old man had a 6-year history of PMR treated with prednisone and cyclosporine. He presented with gait disturbance. Magnetic resonance imaging on the 12th day after the onset of the symptoms showed spinal cord compression caused by a posterior epidural mass at the T5-T6 level.

RESULTS

The patient underwent a T5-T6 laminectomy and a total excision of the mass, which involved the ligament flavum and epidural adipose tissue and firmly attached to the dura mater. Histopathologic examination revealed severe lymphoplasmacytic infiltration with fibrosis in the entire specimen and no evidence of hematomas or tumorous lesions. After surgery, the patient's neurologic symptoms disappeared immediately. Two years after surgery, the patient is neurologically normal and has not had a recurrence.

CONCLUSIONS

This report identifies a rare case of epidural inflammatory pseudotumor in the thoracic spine in a patient with PMR.

摘要

背景

此前仅有 6 例脊柱硬膜外炎症性假瘤的病例报告,且均未发生在巨细胞动脉炎(PMR)的病程中。

目的

描述一例 PMR 患者发生于胸段脊柱的罕见硬膜外炎症性假瘤病例。

研究设计

病例报告。

方法

63 岁男性,PMR 病史 6 年,予泼尼松和环孢素治疗。患者出现步态障碍,症状发作第 12 天行磁共振成像(MRI)检查示 T5-T6 水平硬脊膜外肿块导致脊髓受压。

结果

患者接受 T5-T6 椎板切除术和肿块全切除,肿块累及黄韧带和硬膜外脂肪组织,并与硬脊膜紧密粘连。组织病理学检查显示整个标本中有严重的淋巴浆细胞浸润伴纤维化,无血肿或肿瘤病变的证据。术后,患者的神经症状立即消失。术后 2 年,患者神经功能正常,无复发。

结论

本报告确定了一例 PMR 患者发生于胸段脊柱的罕见硬膜外炎症性假瘤病例。

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