Tabolin V A, Volodin N N
Vestn Akad Med Nauk SSSR. 1990(8):8-14.
The clinical and metabolic adaptation to extrauterine life in preterm was comprehensively evaluated in newborns with 28-34 weeks of gestation. A high incidence of aggravating factors that underlie the development of chronic fetal hypoxia has been revealed. The early neonatal events comprised impairment of cerebral flow, jaundice, oedema, respiratory disorders, infectious toxicosis, the manifestation rate being inversely proportional to the gestational age. A significant immunological impairment was noted along with the serum electrolyte imbalance and changes in bilirubin metabolism. Development and introduction of highly information assessment methods for intrauterine fetal development into practice is essential for the management of very low-birthweight infants. Dynamic follow-up of women at risk of unfavourable pregnancy outcome together with monitoring of the intrauterine fetal development, neonatal adaptation to the extrauterine life, and infants' further development would raise significantly the efficacy of the medical care of mothers and their preterm babies.
对妊娠28 - 34周的早产儿宫外生活的临床和代谢适应性进行了全面评估。已发现慢性胎儿缺氧发展的潜在加重因素发生率很高。早期新生儿事件包括脑血流受损、黄疸、水肿、呼吸障碍、感染性中毒，其表现率与胎龄成反比。还注意到显著的免疫功能损害以及血清电解质失衡和胆红素代谢变化。将高度信息化的宫内胎儿发育评估方法开发并应用于实践对于极低出生体重儿的管理至关重要。对有不良妊娠结局风险的妇女进行动态随访，同时监测宫内胎儿发育、新生儿对宫外生活的适应性以及婴儿的进一步发育，将显著提高对母亲及其早产儿的医疗护理效果。
